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UniProtKB/Swiss-Prot entry Q7TWL9

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNAE2_MYCBO
Primary accession number Q7TWL9
Secondary accession numbers None
Integrated into Swiss-Prot on July 19, 2005
Sequence was last modified on July 19, 2005 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 34)
Name and origin of the protein
Protein name Error-prone DNA polymerase
Synonym EC 2.7.7.7
Gene name
Name: dnaE2
OrderedLocusNames: Mb3405c
From
Mycobacterium bovis [TaxID: 1765] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-935 / AF2122/97;
DOI=10.1073/pnas.1130426100; PubMed=12788972 [NCBI, ExPASy, EBI, Israel, Japan]
Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J., Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
"The complete genome sequence of Mycobacterium bovis.";
Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX248345; CAD95567.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_857046.2; -.
3D structure databases
ModBase Q7TWL9.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003887; Molecular function: DNA-directed DNA polymerase activity (inferred from electronic annotation from HAMAP).
GO:0045020; Biological process: error-prone DNA repair (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01902; -; 1.
PBIL [Tree]
InterPro IPR011708; DNA_pol3_alpha.
IPR004365; NA_bd_OB_tRNA-helicase.
IPR004013; PHP_C.
IPR003141; PHP_N.
IPR004805; PolC_alpha.
Graphical view of domain structure.
Pfam PF07733; DNA_pol3_alpha; 1.
PF02811; PHP; 1.
PF01336; tRNA_anti; 1.
Pfam graphical view of domain structure.
SMART SM00481; POLIIIAc; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00594; polc; 1.
BLOCKS Q7TWL9.
Genome annotation databases
GeneID 1090941; -.
GenomeReviews BX248333_GR; Mb3405c.
KEGG mbo:Mb3405c; -.
Phylogenomic databases
HOGENOM Q7TWL9; -.
Genome annotation databases
CMR Q7TWL9; Mb3405c.
Other
ProtoNet Q7TWL9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   1091  1091     Error-prone DNA polymerase. PRO_0000103383
Sequence information
Length: 1091 AA [This is the length of the unprocessed precursor] Molecular weight: 117784 Da [This is the MW of the unprocessed precursor] CRC64: F4973A856D56711D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MGWSNGPPSW AEMERVLNGK PRHAGVPAFD ADGDVPRSRK RGAYQPPGRE RVGSSVAYAE 

        70         80         90        100        110        120 
LHAHSAYSFL DGASTPEELV EEAARLGLCA LALTDHDGLY GAVRFAEAAA ELDVRTVFGA 

       130        140        150        160        170        180 
ELSLGATART ERPDPPGPHL LVLARGPEGY RRLSRQLAAA HLAGGEKGKP RYDFDALTEA 

       190        200        210        220        230        240 
AGGHWHILTG CRKGHVRQAL SQGGPAAAQR ALADLVDRFT PSRVSIELTH HGHPLDDERN 

       250        260        270        280        290        300 
AALAGLAPRF GVGIVATTGA HFADPSRGRL AMAMAAIRAR RSLDSAAGWL APLGGAHLRS 

       310        320        330        340        350        360 
GEEMARLFAW CPEAVTAAAE LGERCAFGLQ LIAPRLPPFD VPDGHTEDSW LRSLVMAGAR 

       370        380        390        400        410        420 
ERYGPPKSAP RAYSQIEHEL KVIAQLRFPG YFLVVHDITR FCRDNDILCQ GRGSAANSAV 

       430        440        450        460        470        480 
CYALGVTAVD PVANELLFER FLSPARDGPP DIDIDIESDQ REKVIQYVYH KYGRDYAAQV 

       490        500        510        520        530        540 
ANVITYRGRS AVRDMARALG FSPGQQDAWS KQVSHWTGQA DDVDGIPEQV IDLATQIRNL 

       550        560        570        580        590        600 
PRHLGIHSGG MVICDRPIAD VCPVEWARMA NRSVLQWDKD DCAAIGLVKF DLLGLGMLSA 

       610        620        630        640        650        660 
LHYAKDLVAE HKGIEVDLAR LDLSEPAVYE MLARADSVGV FQVESRAQMA TLPRLKPRVF 

       670        680        690        700        710        720 
YDLVVEVALI RPGPIQGGSV HPYIRRRNGV DPVIYEHPSM APALRKTLGV PLFQEQLMQL 

       730        740        750        760        770        780 
AVDCAGFSAA EADQLRRAMG SKRSTERMRR LRGRFYDGMR ALHGAPDEVI DRIYEKLEAF 

       790        800        810        820        830        840 
ANFGFPESHA LSFASLVFYS AWFKLHHPAA FCAALLRAQP MGFYSPQSLV ADARRHGVAV 

       850        860        870        880        890        900 
HGPCVNASLA HATCENAGTE VRLGLGAVRY LGAELAEKLV AERTANGPFT SLPDLTSRVQ 

       910        920        930        940        950        960 
LSVPQVEALA TAGALGCFGM SRREALWAAG AAATGRPDRL PGVGSSSHIP ALPGMSELEL 

       970        980        990       1000       1010       1020 
AAADVWATGV SPDSYPTQFL RADLDAMGVL PAERLGSVSD GDRVLIAGAV THRQRPATAQ 

      1030       1040       1050       1060       1070       1080 
GVTFINLEDE TGMVNVLCTP GVWARHRKLA HTAPALLIRG QVQNASGAIT VVAERMGRLT 

      1090 
LAVGARSRDF R
Q7TWL9 in FASTA format

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