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UniProtKB/Swiss-Prot entry Q7TVB0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GSHB_PROMA
Primary accession number Q7TVB0
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on October 1, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 35)
Name and origin of the protein
Protein name Glutathione synthetase
Synonyms EC 6.3.2.3
Glutathione synthase
GSH synthetase
GSH-S
GSHase
Gene name
Name: gshB
OrderedLocusNames: Pro_0203
From
Prochlorococcus marinus [TaxID: 1219] [HAMAP proteome]
Taxonomy Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae; Prochlorococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SARG / CCMP1375 / SS120;
DOI=10.1073/pnas.1733211100; PubMed=12917486 [NCBI, ExPASy, EBI, Israel, Japan]
Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J., Wincker P., Wolf Y.I., Hess W.R.;
"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome.";
Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017126; AAP99249.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_874597.1; -.
3D structure databases
ModBase Q7TVB0.
Enzyme and pathway databases
BioCyc PMAR167539:PRO_0203-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004363; Molecular function: glutathione synthase activity (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0030145; Molecular function: manganese ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006750; Biological process: glutathione biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00162; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR006284; Glut_synth_pro.
IPR004218; GSHS_ATP_bd.
IPR004215; GSHS_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF02955; GSH-S_ATP; 1.
PF02951; GSH-S_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01380; glut_syn; 1.
PROSITE PS50975; ATP_GRASP; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q7TVB0.
ProtoNet Q7TVB0.
Genome annotation databases
GeneID 1461582; -.
GenomeReviews AE017126_GR; Pro_0203.
KEGG pma:Pro0203; -.
Phylogenomic databases
HOGENOM Q7TVB0; -.
Genome annotation databases
CMR Q7TVB0; Pro_0203.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Glutathione biosynthesis; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   308  308     Glutathione synthetase. PRO_0000197473
DOMAIN   120   304  185     ATP-grasp. 
NP_BIND   146   202  57     ATP (By similarity). 
METAL   275   275        Magnesium or manganese (By similarity). 
METAL   277   277        Magnesium or manganese (By similarity). 
Sequence information
Length: 308 AA [This is the length of the unprocessed precursor] Molecular weight: 33535 Da [This is the MW of the unprocessed precursor] CRC64: 9AFFE358F9776F5D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKQLFILDPI ELINPAKDSS AALMQAAHRA SLDIWVCTPA DLQAKGAKAR VVAKTIVPEP 

        70         80         90        100        110        120 
WKSLGEAQNL SLNEFHCIWM RKDPPVDEAF LYATHLLEVA ERAGVLVLNK PASLRAWNEK 

       130        140        150        160        170        180 
LGALRFSKLM APTLVASRVN ELKEFAKEQG EVVLKPLGGK GGQGVIRVAD AALGLDALLE 

       190        200        210        220        230        240 
LVTSQEQMPV MMQKFLPKVI EGDKRILLVN GEPLGAINRL PKCGDFRSNL ALGGQAEATN 

       250        260        270        280        290        300 
LSKREKEICE ELGPSLKSEG LFFVGIDVIG GMLSEINVTS PTGVREVEKL MNIPLADQVI 


ERLLANFS
Q7TVB0 in FASTA format

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