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UniProtKB/Swiss-Prot entry Q7RYU8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HAT1_NEUCR
Primary accession number Q7RYU8
Secondary accession numbers None
Integrated into Swiss-Prot on March 21, 2006
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 29)
Name and origin of the protein
Protein name Histone acetyltransferase type B catalytic subunit
Synonym EC 2.3.1.48
Gene name
Name: hat-1
ORFNames: NCU06472
From
Neurospora crassa [TaxID: 5141] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
DOI=10.1038/nature01554; PubMed=12712197 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
"The genome sequence of the filamentous fungus Neurospora crassa.";
Nature 422:859-868(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AABX02000027; EAA28127.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_957363.1; -.
3D structure databases
HSSP Q12341; 1BOB. [HSSP ENTRY / PDB]
ModBase Q7RYU8.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005634; Cellular component: nucleus (inferred from electronic annotation from UniProtKB-KW).
GO:0004402; Molecular function: histone acetyltransferase activity (inferred from electronic annotation from EC).
GO:0016568; Biological process: chromatin modification (inferred from electronic annotation from UniProtKB-KW).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR016181; Acyl_CoA_acyltransferase.
IPR017380; Hist_AcTrfase_B-typ_cat_su.
Graphical view of domain structure.
Gene3D G3DSA:3.40.630.30; Acyl_CoA_acyltransferase; 1.
PIRSF PIRSF038084; HAT-B_cat; 1.
BLOCKS Q7RYU8.
ProtoNet Q7RYU8.
Genome annotation databases
GeneID 3873462; -.
KEGG ncr:NCU06472; -.
NMPDR fig|5141.1.peg.4260; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acyltransferase; Chromatin regulator; Complete proteome; Cytoplasm; DNA damage; DNA repair; Nucleus; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   508  508     Histone acetyltransferase type B catalytic subunit. PRO_0000227726
Sequence information
Length: 508 AA [This is the length of the unprocessed precursor] Molecular weight: 57696 Da [This is the MW of the unprocessed precursor] CRC64: D2DCF7829D6855D7 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSGDDDWWTS SNEALLVSLV TPSDTGVKTL DTFHPEYTNN IFGEKEQIFG YKGLRINLQY 

        70         80         90        100        110        120 
NASDMLPNLK VSYKKKYQPT ADEEALDINE VLSEFLPEIA FQKQSDFETR LKSIPDNWTP 

       130        140        150        160        170        180 
PGTLVTSFTN KDGEYEVYSG KITDPAVKQL LNRIQILVPF FVDGGTPIDM EDPDVDRWTI 

       190        200        210        220        230        240 
YFLYNKRPLL NQPDKFSYHF AGYSTLYRYY AFQPPAESES KTPTDTPTFS VDGDFDLDTL 

       250        260        270        280        290        300 
PCRTRISQFI IIPPFQQKGL GSRLYSIIYQ QYLKHEPTIE LTVEDPNEAF DDMRDLADLA 

       310        320        330        340        350        360 
FLSKQPEFQA LKIDTSVEIP EEGKAPSNIV DQAAWEACRK KFKIVPRQFA RVLEMYLMSQ 

       370        380        390        400        410        420 
LPESVRPGLG APEDEDYEEQ SGRSKSKGHE KALPKPTPED EHTYRLWMML VKRRLYVHNR 

       430        440        450        460        470        480 
DALGQLELKE RREELAKVFA GVEFDYARLL IKAEEQGKLA QADGETAGDQ VPATPSAANG 

       490        500 
KRKLDEVEQA EGTAAASSKK AKVESGHA 

Q7RYU8 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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