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UniProtKB/Swiss-Prot entry Q7RYE7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GAL7_NEUCR
Primary accession number Q7RYE7
Secondary accession numbers None
Integrated into Swiss-Prot on September 27, 2004
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 40)
Name and origin of the protein
Protein name Galactose-1-phosphate uridylyltransferase
Synonyms Gal-1-P uridylyltransferase
EC 2.7.7.12
UDP-glucose--hexose-1-phosphate uridylyltransferase
Gene name
Name: gal-7
ORFNames: G21B4.010, NCU04460
From
Neurospora crassa [TaxID: 5141] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
DOI=10.1093/nar/gkg293; PubMed=12655011 [NCBI, ExPASy, EBI, Israel, Japan]
Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D., Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
"What's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence.";
Nucleic Acids Res. 31:1944-1954(2003).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
DOI=10.1038/nature01554; PubMed=12712197 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
"The genome sequence of the filamentous fungus Neurospora crassa.";
Nature 422:859-868(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX908808; CAF05986.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AABX02000020; EAA27793.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_957029.1; -.
3D structure databases
ModBase Q7RYE7.
Ontologies
GO
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001937; GalP_UDPtransf1.
IPR005850; GalP_Utransf_C.
IPR005849; GalP_Utransf_N.
IPR011151; His_triad_motif.
Graphical view of domain structure.
Gene3D G3DSA:3.30.428.10; His_triad_motif; 2.
PANTHER PTHR11943; GalP_UDPtransf1; 1.
Pfam PF02744; GalP_UDP_tr_C; 1.
PF01087; GalP_UDP_transf; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000808; GalT; 1.
ProDom PD005051; GalP_Utransf; 2.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00209; galT_1; 1.
PROSITE PS00117; GAL_P_UDP_TRANSF_I; 1.
BLOCKS Q7RYE7.
ProtoNet Q7RYE7.
Genome annotation databases
GeneID 3873213; -.
KEGG ncr:NCU04460; -.
NMPDR fig|5141.1.peg.1746; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Complete proteome; Galactose metabolism; Iron; Metal-binding; Nucleotidyltransferase; Transferase; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   392  392     Galactose-1-phosphate uridylyltransferase. PRO_0000169890
ACT_SITE   207   207        Tele-UMP-histidine intermediate (By similarity). 
METAL   52    52        Zinc (By similarity). 
METAL   55    55        Zinc (By similarity). 
METAL   126   126        Zinc (By similarity). 
METAL   205   205        Zinc (By similarity). 
METAL   223   223        Iron (By similarity). 
METAL   323   323        Iron (By similarity). 
METAL   340   340        Iron (By similarity). 
METAL   342   342        Iron (By similarity). 
Sequence information
Length: 392 AA [This is the length of the unprocessed precursor] Molecular weight: 44890 Da [This is the MW of the unprocessed precursor] CRC64: F7716BC5E28B4335 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTDKVLDDIS HRRYNPLNGS WLLVSPHRTK RPWQGQQEAP ALNKLPEYDP QCYLCPGNKR 

        70         80         90        100        110        120 
AQGDSNPHYK NTFAFVNDYS AVKEEQQEYH PRKDAAGDGD DDIASLLLQA QPATGRCYVL 

       130        140        150        160        170        180 
TFSAKHDTTL ADMSATEIVP VIETWTRIYA SHLSASHPLR DAAARSLSEI PPNPDGEVEP 

       190        200        210        220        230        240 
AKKQQLRYMQ IFENKGAAMG CSNPHPHCQI WTTSTLPEEP GKELAQMTKY HREHKGRHLL 

       250        260        270        280        290        300 
EDYVKVEMAK GERVVWQNDG FLVVCPWWAV WPFEVLVIAK RHVRALVELT SEERLQFAEA 

       310        320        330        340        350        360 
VQEVTRRYDN LFETNFPYSS GIHQAPLDCT EEEAETSWFH MHFYPPLLRS ATVRKFLVGY 

       370        380        390 
ELMAEPQRDI TPEQAAARLR DCGGELYRKS LQ 

Q7RYE7 in FASTA format

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