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UniProtKB/Swiss-Prot entry Q7P0M1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PUR9_CHRVO
Primary accession number Q7P0M1
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 30)
Name and origin of the protein
Protein name Bifunctional purine biosynthesis protein purH
Synonyms None
Includes Phosphoribosylaminoimidazolecarboxamide formyltransferase
     (EC 2.1.2.3)
     (AICAR transformylase)
IMP cyclohydrolase
     (EC 3.5.4.10)
     (Inosinicase)
     (IMP synthetase)
     (ATIC)
Gene name
Name: purH
OrderedLocusNames: CV_0546
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ58222.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_900216.1; -.
3D structure databases
HSSP P31939; 1PKX. [HSSP ENTRY / PDB]
ModBase Q7P0M1.
Enzyme and pathway databases
BioCyc CVIO243365:CV_0546-MON; -.
Ontologies
GO
GO:0003937; Molecular function: IMP cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0004643; Molecular function: phosphoribosylaminoimidazolecarboxamide formyltransferase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00139; -; 1.
PBIL [Tree]
InterPro IPR002695; AICARFT_IMPCHas.
IPR013982; AICARFT_IMPCHas_formly.
IPR011607; MGS.
Graphical view of domain structure.
PANTHER PTHR11692; AICARFT_IMPCHas; 1.
Pfam PF01808; AICARFT_IMPCHas; 1.
PF02142; MGS; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000414; AICARFT_IMPCHas; 1.
SMART SM00798; AICARFT_IMPCHas; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00355; purH; 1.
BLOCKS Q7P0M1.
ProtoNet Q7P0M1.
Genome annotation databases
GeneID 2547879; -.
GenomeReviews AE016825_GR; CV_0546.
KEGG cvi:CV_0546; -.
NMPDR fig|243365.1.peg.546; -.
Phylogenomic databases
HOGENOM Q7P0M1; -.
Genome annotation databases
CMR Q7P0M1; CV_0546.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Multifunctional enzyme; Purine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   525  525     Bifunctional purine biosynthesis protein purH. PRO_1000018873
Sequence information
Length: 525 AA [This is the length of the unprocessed precursor] Molecular weight: 56042 Da [This is the MW of the unprocessed precursor] CRC64: 84D5028653B41459 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTKIERALIS VSDKNGVLEF ARELSALGVH ILSTGGTAKL LLEAGLPVTE VSDYTGFPEM 

        70         80         90        100        110        120 
LDGRVKTLHP KVHGGILGRR DLPEHVATMA EHGIGNIDLV CVNLYPFEAT VANPDCSLED 

       130        140        150        160        170        180 
AIENIDIGGP TMVRSAAKNW AHVAIVTDSA DYPALVGELK ANGGRLAKAT RFELAKKAFT 

       190        200        210        220        230        240 
HTAAYDGAIS NYLTSLAEGV VAGKPERVAF PNRLNAQFIK VQDMRYGENP HQAAAFYRDL 

       250        260        270        280        290        300 
DPAAGSIAHY KQLQGKELSY NNIADADAAW EAVKTFEQTA CVIVKHANPC GVAVGPDTLS 

       310        320        330        340        350        360 
AYKLAFATDT TSAFGGIIAF NRPVDAATVE AVTGQFLEVL IAPSFTEEAK AIIAAKKNVR 

       370        380        390        400        410        420 
VLEIPLESGA NRFELKRVGG GVLVQTPDIR NVGLDELRVV SKRQPTPQEM SDLLFAWRVA 

       430        440        450        460        470        480 
KFVKSNAIVF CKDGQTAGIG AGQMSRVDST RIAARKAQDA GLSLAGAVAA SDAFFPFRDG 

       490        500        510        520 
IDVIAEQGIK AIIQPGGSMR DEEVFAAADE HGIALVLTGV RHFRH 

Q7P0M1 in FASTA format

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