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UniProtKB/Swiss-Prot entry Q7P0E6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HIS2_CHRVO
Primary accession number Q7P0E6
Secondary accession numbers None
Integrated into Swiss-Prot on March 15, 2004
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 42)
Name and origin of the protein
Protein name Phosphoribosyl-ATP pyrophosphatase
Synonyms PRA-PH
EC 3.6.1.31
Gene name
Name: hisE
OrderedLocusNames: CV_0621
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ58297.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_900291.1; -.
3D structure databases
PDB
2A7W; X-ray; 2.80 A; A/B/C/D/E/F/G/H/I/J/K/L=1-108.[ExPASy / RCSB / EBI]
PDBsum 2A7W; -.
ModBase Q7P0E6.
Enzyme and pathway databases
BioCyc CVIO243365:CV_0621-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004636; Molecular function: phosphoribosyl-ATP diphosphatase activity (inferred from electronic annotation from HAMAP).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01020; -; 1.
PBIL [Tree]
InterPro IPR008179; PRib-ATP_pyrophosphohydrolase.
Graphical view of domain structure.
Pfam PF01503; PRA-PH; 1.
Pfam graphical view of domain structure.
ProDom PD002611; Pra_PH/CH; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR03188; histidine_hisI; 1.
BLOCKS Q7P0E6.
ProtoNet Q7P0E6.
Genome annotation databases
GeneID 2550491; -.
GenomeReviews AE016825_GR; CV_0621.
KEGG cvi:CV_0621; -.
NMPDR fig|243365.1.peg.621; -.
Phylogenomic databases
HOGENOM Q7P0E6; -.
Other
LinkHub Q7P0E6; -.
Genome annotation databases
CMR Q7P0E6; CV_0621.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Amino-acid biosynthesis; Complete proteome; Cytoplasm; Histidine biosynthesis; Hydrolase.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   108  108     Phosphoribosyl-ATP pyrophosphatase. PRO_0000136356
HELIX   6    15  10      
HELIX   16    18  3      
TURN   21    23  3      
HELIX   25    32  8      
HELIX   34    53  20      
HELIX   57    77  21      
HELIX   82    92  11      
Sequence information
Length: 108 AA [This is the length of the unprocessed precursor] Molecular weight: 12139 Da [This is the MW of the unprocessed precursor] CRC64: F1A172FD0CA204D4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTPDVLKNIA DTLEARREAA PQSSYVASLF HKGEDAILKK VAEEAAETLM ASKDKDKLHL 

        70         80         90        100 
VREVADLWFH TMVLLTYHGL RPEDVVMELH RREGISGLDE KASRKPTA 

Q7P0E6 in FASTA format

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