ID   NTPA_CHRVO              Reviewed;         197 AA.
AC   Q7NZJ6;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   22-JUL-2008, entry version 33.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=NTPase;
GN   OrderedLocusNames=CV_0926;
OS   Chromobacterium violaceum.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
OC   Neisseriaceae; Chromobacterium.
OX   NCBI_TaxID=536;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
RX   MEDLINE=22882880; PubMed=14500782; DOI=10.1073/pnas.1832124100;
RA   Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T.,
RA   Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R.,
RA   Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F.,
RA   Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M.,
RA   Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S.,
RA   Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A.,
RA   Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M.,
RA   Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O.,
RA   Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L.,
RA   Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A.,
RA   Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R.,
RA   Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B.,
RA   Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J.,
RA   Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P.,
RA   Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S.,
RA   di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M.,
RA   Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C.,
RA   Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O.,
RA   Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P.,
RA   Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E.,
RA   Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N.,
RA   Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C.,
RA   Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L.,
RA   Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T.,
RA   Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
RT   "The complete genome sequence of Chromobacterium violaceum reveals
RT   remarkable and exploitable bacterial adaptability.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; AE016825; AAQ58600.1; -; Genomic_DNA.
DR   RefSeq; NP_900596.1; -.
DR   HSSP; P52061; 1K7K.
DR   GeneID; 2550964; -.
DR   GenomeReviews; AE016825_GR; CV_0926.
DR   KEGG; cvi:CV_0926; -.
DR   NMPDR; fig|243365.1.peg.926; -.
DR   HOGENOM; Q7NZJ6; -.
DR   BioCyc; CVIO243365:CV_0926-MON; -.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p_like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
DR   TIGRFAMs; TIGR00042; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    197       Nucleoside-triphosphatase.
FT                                /FTId=PRO_0000178153.
SQ   SEQUENCE   197 AA;  21183 MW;  2175D83FA46865C9 CRC64;
     MFDQLVLASN NAGKLKEFGA LFAELGVTVR PQRDFDVPEC PEPHHTFLEN ALEKARHASR
     LTGLPALADD SGICVEALGG APGVFSARFA GEPKSDARNN ALLVEKLQGE ANRRAWYYCV
     LVLVRHADDP QPLVADGIWL GEVRDEAAGE GGFGYDPHFH LPGYGVSVAE LDAAEKNRVS
     HRGQALAALM AKLKALA
//