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UniProtKB/Swiss-Prot entry Q7NVY8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DXR_CHRVO
Primary accession number Q7NVY8
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 35)
Name and origin of the protein
Protein name 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms DXP reductoisomerase
EC 1.1.1.267
1-deoxyxylulose-5-phosphate reductoisomerase
2-C-methyl-D-erythritol 4-phosphate synthase
Gene name
Name: dxr
OrderedLocusNames: CV_2202
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ59875.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_901872.1; -.
3D structure databases
ModBase Q7NVY8.
Enzyme and pathway databases
BioCyc CVIO243365:CV_2202-MON; -.
Ontologies
GO
GO:0030604; Molecular function: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0016114; Biological process: terpenoid biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00183; -; 1.
PBIL [Tree]
InterPro IPR003821; DXP_reductoisomerase.
IPR013644; DXP_reductoisomerase_C.
IPR013512; DXP_reductoisomerase_N.
Graphical view of domain structure.
Pfam PF08436; DXP_redisom_C; 1.
PF02670; DXP_reductoisom; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF006205; Dxp_reductismrs; 1.
TIGRFAMs TIGR00243; Dxr; 1.
BLOCKS Q7NVY8.
ProtoNet Q7NVY8.
Genome annotation databases
GeneID 2549212; -.
GenomeReviews AE016825_GR; CV_2202.
KEGG cvi:CV_2202; -.
NMPDR fig|243365.1.peg.2202; -.
Phylogenomic databases
HOGENOM Q7NVY8; -.
Genome annotation databases
CMR Q7NVY8; CV_2202.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Isoprene biosynthesis; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   394  394     1-deoxy-D-xylulose 5-phosphate reductoisomerase. PRO_0000163635
NP_BIND   10    39  30     NADP (By similarity). 
METAL   153   153        Divalent metal cation (By similarity). 
METAL   155   155        Divalent metal cation (By similarity). 
METAL   229   229        Divalent metal cation (By similarity). 
BINDING   128   128        Substrate (By similarity). 
BINDING   155   155        Substrate (By similarity). 
BINDING   184   184        Substrate (By similarity). 
BINDING   207   207        Substrate (By similarity). 
BINDING   229   229        Substrate (By similarity). 
Sequence information
Length: 394 AA [This is the length of the unprocessed precursor] Molecular weight: 41674 Da [This is the MW of the unprocessed precursor] CRC64: 482DEAA31A2275F0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTKPQGIAVL GATGSVGCNT LDVVARHPER YRVVALTAHR QLDKLFEQAR RFCPDYLVVA 

        70         80         90        100        110        120 
DADAAARLRA RLAEAGLRSE VLHGADALVQ VAALPEVDAV MASIVGAAGL PSALAAARAG 

       130        140        150        160        170        180 
KRILLANKES LVVAGRLFMD AVRASGSALL PVDSEHSAIF QSLPADYAGN PDGAGVRKII 

       190        200        210        220        230        240 
LTASGGPFRN RPAADLAHVT PDEACRHPNW SMGRKISVDS ATLMNKGLEV IEARWLFNVP 

       250        260        270        280        290        300 
PSRIEVAVHP QSVIHSMVQY RDGSVMAQLG SPDMRTPIAC ALAWPERIDA GVEPMDFFSL 

       310        320        330        340        350        360 
SDLTFEKPDL ERFPCLQLAF DALEMGGDAP AVLNAANEVA VAAFLAGRLR FVDIPRVVAA 

       370        380        390 
SLSGVSCAAS DSLEGLLARD EEARRFAEGG VAAC 

Q7NVY8 in FASTA format

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