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UniProtKB/Swiss-Prot entry Q7NV72


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DDLA_CHRVO
Primary accession number Q7NV72
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 40)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase A
Synonyms EC 6.3.2.4
D-alanylalanine synthetase A
D-Ala-D-Ala ligase A
Gene name
Name: ddlA
OrderedLocusNames: CV_2472
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ60143.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_902142.1; -.
3D structure databases
ModBase Q7NV72.
Enzyme and pathway databases
BioCyc CVIO243365:CV_2472-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q7NV72.
Genome annotation databases
GeneID 2548937; -.
GenomeReviews AE016825_GR; CV_2472.
KEGG cvi:CV_2472; -.
NMPDR fig|243365.1.peg.2472; -.
Phylogenomic databases
HOGENOM Q7NV72; -.
Genome annotation databases
CMR Q7NV72; CV_2472.
Other
ProtoNet Q7NV72.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   366  366     D-alanine--D-alanine ligase A. PRO_0000177805
DOMAIN   145   348  204     ATP-grasp. 
NP_BIND   175   230  56     ATP (By similarity). 
METAL   302   302        Magnesium or manganese 1 (By similarity). 
METAL   315   315        Magnesium or manganese 1 (By similarity). 
METAL   315   315        Magnesium or manganese 2 (By similarity). 
METAL   317   317        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 366 AA [This is the length of the unprocessed precursor] Molecular weight: 39309 Da [This is the MW of the unprocessed precursor] CRC64: 606E4CD5C8E058C9 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGKIRVGLIF GGQSSEHEVS LQSARNILQA IDGERFEVSL IGVDKQGRWH ASQASNFLLN 

        70         80         90        100        110        120 
ADDPGRIALR ESGENLALVP GECSGQLQTA ANAHPLAQID VAFPIVHGTL GEDGSLQGLL 

       130        140        150        160        170        180 
RMANIPFVGA GVLGSAVCMD KDVAKRLLRD AGLKVAPFVS LTRSKAAGAD LSAIVEQLGL 

       190        200        210        220        230        240 
PLFVKPANQG SSVGVSKVKR EADLRAALDE AFRYDHKVLV EQAVIGREIE CAVLGNERPR 

       250        260        270        280        290        300 
ASGCGEIVLS DEFYAYDTKY LNEDGARVAV PADIPDEACQ RIRGIAIEAF QALECSGMAR 

       310        320        330        340        350        360 
VDVFLTPDGE VVINELNTLP GFTNISMYPK LWQAAGMSYR ELITALIELA LEKGRMDEAL 


SRSCQY 

Q7NV72 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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