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UniProtKB/Swiss-Prot entry Q7NS98


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PURA2_CHRVO
Primary accession number Q7NS98
Secondary accession numbers None
Integrated into Swiss-Prot on April 13, 2004
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 45)
Name and origin of the protein
Protein name Adenylosuccinate synthetase 2
Synonyms EC 6.3.4.4
IMP--aspartate ligase 2
AdSS 2
AMPSase 2
Gene name
Name: purA2
OrderedLocusNames: CV_3528
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ61190.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_903198.1; -.
3D structure databases
ModBase Q7NS98.
Enzyme and pathway databases
BioCyc CVIO243365:CV_3528-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004019; Molecular function: adenylosuccinate synthase activity (inferred from electronic annotation from HAMAP).
GO:0005525; Molecular function: GTP binding (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from HAMAP).
GO:0006164; Biological process: purine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00011; atypical; 1.
PBIL [Tree]
InterPro IPR001114; AdlSucc_Synth.
Graphical view of domain structure.
PANTHER PTHR11846; Asucc_synthtase; 1.
Pfam PF00709; Adenylsucc_synt; 1.
Pfam graphical view of domain structure.
ProDom PD001188; Asucc_synthtase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00788; Adenylsucc_synt; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00184; purA; 1.
PROSITE PS01266; ADENYLOSUCCIN_SYN_1; 1.
PS00513; ADENYLOSUCCIN_SYN_2; 1.
BLOCKS Q7NS98.
ProtoNet Q7NS98.
Genome annotation databases
GeneID 2547652; -.
GenomeReviews AE016825_GR; CV_3528.
KEGG cvi:CV_3528; -.
NMPDR fig|243365.1.peg.3528; -.
Phylogenomic databases
HOGENOM Q7NS98; -.
Genome annotation databases
CMR Q7NS98; CV_3528.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; GTP-binding; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   431  431     Adenylosuccinate synthetase 2. PRO_0000095166
NP_BIND   13    19  7     GTP (Potential). 
ACT_SITE   141   141        By similarity. 
ACT_SITE   148   148        By similarity. 
METAL   14    14        Magnesium (By similarity). 
METAL   41    41        Magnesium; via carbonyl oxygen (By similarity). 
Sequence information
Length: 431 AA [This is the length of the unprocessed precursor] Molecular weight: 46638 Da [This is the MW of the unprocessed precursor] CRC64: 373EE33F255E64BB [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSKNVVVIGT QWGDEGKGKI VDWLTDHARA VVRFQGGHNA GHTLWVNGKK TVVRLVPSGI 

        70         80         90        100        110        120 
LRPDVECFIG NGVVLSPEAL LKEIDELEAA GVNASARLKI AEGCPLILPY HIALDQAREA 

       130        140        150        160        170        180 
AKGDAKIGTT GRGIGPCYED KVARRALKVI DLFDPARFET KLKENVDYYN FLLTNLFKAE 

       190        200        210        220        230        240 
PVSYEAILAD TMKMAERIKP MVADVSRTLY DLDKAGTPIL FEGAQGTLLD IDHGTYPYVT 

       250        260        270        280        290        300 
SSNCVAGAAA PGAGVPPQML NYVLGIVKGY ATRVGSGPFP TEQENEIGAF LAKRGNEFGS 

       310        320        330        340        350        360 
VTGRPRRCGW FDAAALKRSI QINGVSGLCV MKLDVMDGLE EIKLCTGYML DGQKVDILPF 

       370        380        390        400        410        420 
GSDAVTKCEP VYETLPGWTG TTVGVKRWED LPANAQAYLK RIEEVCGAPV DIVSTGPDRE 

       430 
ETIVLRHPFG L 

Q7NS98 in FASTA format

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