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UniProtKB/Swiss-Prot entry Q7NQ65


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GSHB_CHRVO
Primary accession number Q7NQ65
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 35)
Name and origin of the protein
Protein name Glutathione synthetase
Synonyms EC 6.3.2.3
Glutathione synthase
GSH synthetase
GSH-S
GSHase
Gene name
Name: gshB
OrderedLocusNames: CV_4275
From
Chromobacterium violaceum [TaxID: 536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Chromobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131;
DOI=10.1073/pnas.1832124100; PubMed=14500782 [NCBI, ExPASy, EBI, Israel, Japan]
Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A., van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.;
"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability.";
Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016825; AAQ61935.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_903945.1; -.
3D structure databases
ModBase Q7NQ65.
Enzyme and pathway databases
BioCyc CVIO243365:CV_4275-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004363; Molecular function: glutathione synthase activity (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0030145; Molecular function: manganese ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006750; Biological process: glutathione biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00162; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR006284; Glut_synth_pro.
IPR004218; GSHS_ATP_bd.
IPR004215; GSHS_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF02955; GSH-S_ATP; 1.
PF02951; GSH-S_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01380; glut_syn; 1.
PROSITE PS50975; ATP_GRASP; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q7NQ65.
ProtoNet Q7NQ65.
Genome annotation databases
GeneID 2548852; -.
GenomeReviews AE016825_GR; CV_4275.
KEGG cvi:CV_4275; -.
NMPDR fig|243365.1.peg.4275; -.
Phylogenomic databases
HOGENOM Q7NQ65; -.
Genome annotation databases
CMR Q7NQ65; CV_4275.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Glutathione biosynthesis; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   314  314     Glutathione synthetase. PRO_0000197463
DOMAIN   122   309  188     ATP-grasp. 
NP_BIND   149   206  58     ATP (By similarity). 
METAL   280   280        Magnesium or manganese (By similarity). 
METAL   282   282        Magnesium or manganese (By similarity). 
Sequence information
Length: 314 AA [This is the length of the unprocessed precursor] Molecular weight: 35087 Da [This is the MW of the unprocessed precursor] CRC64: CAEB175EC4C135E2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRILFIADPL EHFKIYKDTT FAMMEEAHRR GHAISFAEAH QLSVEGGRLQ VDACDLAVTD 

        70         80         90        100        110        120 
ERPDWYKLGP KLRQPLTAFS AVVMRKDPPF DMEYLYASQL FTLAEAQGVK VFTSGQALRD 

       130        140        150        160        170        180 
FNEKLAILHF PELISPTLIS GEAHRLRAFV NQHQDVILKP LDSMGGDSIF RVKPDDPNLS 

       190        200        210        220        230        240 
VIIETITWRG KRTVMAQRYI PEIRDGDKRI LVIDGVPVDH CLARIPAAGE TRGNLAAGGR 

       250        260        270        280        290        300 
GEARPLSARD REIAETVGPE LKKRGILLAG LDVIGNYLTE VNVTSPTCFR EIMDQTGVNV 

       310 
AGLYIDALER RCQH 

Q7NQ65 in FASTA format

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