ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q7N7A4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name GSH1_PHOLL
Primary accession number Q7N7A4
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 2004
Sequence was last modified on December 15, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 30)
Name and origin of the protein
Protein name Glutamate--cysteine ligase
Synonyms EC 6.3.2.2
Gamma-glutamylcysteine synthetase
Gamma-ECS
GCS
Gene name
Name: gshA
OrderedLocusNames: plu1252
From
Photorhabdus luminescens subsp. laumondii [TaxID: 141679] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Photorhabdus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=TT01;
DOI=10.1038/nbt886; PubMed=14528314 [NCBI, ExPASy, EBI, Israel, Japan]
Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C., Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., Kunst F.;
"The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens.";
Nat. Biotechnol. 21:1307-1313(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX571863; CAE13546.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_928563.1; -.
3D structure databases
ModBase Q7N7A4.
Enzyme and pathway databases
BioCyc PLUM243265:PLU1252-MON; -.
Organism-specific databases
PhotoList plu1252; -.
Ontologies
GO
GO:0004357; Molecular function: glutamate-cysteine ligase activity (inferred from electronic annotation from HAMAP).
GO:0006750; Biological process: glutathione biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00578; -; 1.
PBIL [Tree]
InterPro IPR007370; Glu_cys_ligase.
IPR006334; Glut_cys_ligase.
Graphical view of domain structure.
Pfam PF04262; Glu_cys_ligase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01434; glu_cys_ligase; 1.
BLOCKS Q7N7A4.
ProtoNet Q7N7A4.
Genome annotation databases
GeneID 2801220; -.
GenomeReviews BX470251_GR; plu1252.
KEGG plu:plu1252; -.
NMPDR fig|243265.1.peg.1187; -.
Phylogenomic databases
HOGENOM Q7N7A4; -.
Genome annotation databases
CMR Q7N7A4; plu1252.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glutathione biosynthesis; Ligase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   519  519     Glutamate--cysteine ligase. PRO_0000192530
Sequence information
Length: 519 AA [This is the length of the unprocessed precursor] Molecular weight: 58738 Da [This is the MW of the unprocessed precursor] CRC64: 4F478A73A07BB2C0 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIPDVSRALS WLEAHPTILK GIRRGVERET LRITSDGSLA ITEHPKTLGA ALTHKWITTD 

        70         80         90        100        110        120 
FAESLLEFIT PAGDDIKYTI SFLSDIHRHT ARVLDKEKMW PLSMPCFIDA EENITLAQYG 

       130        140        150        160        170        180 
ASNVGRYKTL YREGLKNRYG ALMQTISGVH YNFSLPIEFW RAWVGVEDAE SGKEQISNGY 

       190        200        210        220        230        240 
FRLIRNYYRF GWVIPYLFGA SPAICSSFLR GRETSFLFER TEDGTCYLPY ATSLRMSNLG 

       250        260        270        280        290        300 
YTNKSQSDLN ITFNNLHTYI DGLKKAIHKP SDEFAKLGTK QGDKHIQLNT NVLQIENELY 

       310        320        330        340        350        360 
APIRPKRVTR GNESPSDALL RGGVEYIEVR SLDINPFAAI GVNETQIRFL DLFLIWCVLA 

       370        380        390        400        410        420 
EAPEMGSDEL DCCRKNWNRV ILEGRKPGQM IGLGCGSVEE PLAKVGKKLF SDLKRVAAIL 

       430        440        450        460        470        480 
DSCSGTQYQK VCEELIATFD DSSLTLSARV LEKMKSQGIG GFGLELADEY HQQLISEKYE 

       490        500        510 
VISDEQFAIE RRASVERQDA LEREDTMSFD EYLKQQTGC
Q7N7A4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!