ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q7CWK7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MDH_AGRT5
Primary accession number Q7CWK7
Secondary accession number Q8UC59
Integrated into Swiss-Prot on August 16, 2004
Sequence was last modified on August 16, 2004 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 34)
Name and origin of the protein
Protein name Malate dehydrogenase
Synonym EC 1.1.1.37
Gene name
Name: mdh
OrderedLocusNames: Atu2639
ORFNames: AGR_C_4782
From
Agrobacterium tumefaciens (strain C58 / ATCC 33970) [TaxID: 176299] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE007869; AAK88360.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AF2900; AF2900.
G97675; G97675.
RefSeq NP_355575.2; -.
3D structure databases
HSSP P80040; 1GUY. [HSSP ENTRY / PDB]
ModBase Q7CWK7.
Ontologies
GO
GO:0030060; Molecular function: L-malate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006099; Biological process: tricarboxylic acid cycle (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00487; -; 1.
PBIL [Tree]
InterPro IPR001557; L-lactate/malate_DHase.
IPR001236; Lactate/malate_DHase.
IPR015955; Lactate_DHase/Glyco_Ohase_4_C.
IPR001252; Malate_DHase_AS.
IPR011275; Malate_DHase_NAD-dep_bac.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.90.110.10; lact_mal_DH; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02866; Ldh_1_C; 1.
PF00056; Ldh_1_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000102; Lac_mal_DH; 1.
PRINTS PR00086; LLDHDRGNASE.
TIGRFAMs TIGR01763; MalateDH_bact; 1.
BLOCKS Q7CWK7.
Genome annotation databases
GeneID 1134677; -.
GenomeReviews AE007869_GR; Atu2639.
KEGG atc:AGR_C_4782; -.
atu:Atu2639; -.
Phylogenomic databases
HOGENOM Q7CWK7; -.
Genome annotation databases
CMR Q7CWK7; Atu2639.
Other
ProtoNet Q7CWK7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   320  320     Malate dehydrogenase. PRO_0000113419
NP_BIND   10    15  6     NAD (By similarity). 
NP_BIND   119   121  3     NAD (By similarity). 
ACT_SITE   176   176        Proton acceptor (By similarity). 
BINDING   34    34        NAD (By similarity). 
BINDING   83    83        Substrate (By similarity). 
BINDING   89    89        Substrate (By similarity). 
BINDING   96    96        NAD (By similarity). 
BINDING   121   121        Substrate (By similarity). 
BINDING   152   152        Substrate (By similarity). 
Sequence information
Length: 320 AA [This is the length of the unprocessed precursor] Molecular weight: 33537 Da [This is the MW of the unprocessed precursor] CRC64: 3073A7C3BC0FCE5E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MARKKIALIG SGMIGGTLAH LASLKELGDI VLFDIADGIP QGKGLDIAQS GPVEGFNAKL 

        70         80         90        100        110        120 
SGASDYAAIE GADVCIVTAG VARKPGMSRD DLLGINLKVM EQVGAGIKKY APNAFVICIT 

       130        140        150        160        170        180 
NPLDAMVWAL QKFSGLPKNK VVGMAGVLDS ARFRLFLAEE FNVSVQDVTA FVLGGHGDTM 

       190        200        210        220        230        240 
VPLARYSTVG GVPLTDLVKM GWLTAERLEQ IIQRTRDGGA EIVGLLKTGS AYYAPAASAI 

       250        260        270        280        290        300 
EMAESYLKDK KRVLPAAAHL SGQYGVDDMY VGVPTIIGAG GIERVIEIEL NKEEEAAFQK 

       310        320 
SVGAVAGLCE ACINIAPSLK 

Q7CWK7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ch flag SIB Switzerland Mirror sites: Australia  Brazil  Canada  China  Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!