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UniProtKB/Swiss-Prot entry Q73A47


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC2_BACC1
Primary accession number Q73A47
Secondary accession numbers None
Integrated into Swiss-Prot on July 19, 2004
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 35)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase 2
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase 2
Alpha-keto-beta-hydroxylacil reductoisomerase 2
Gene name
Name: ilvC2
OrderedLocusNames: BCE_1936
From
Bacillus cereus (strain ATCC 10987) [TaxID: 222523] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/nar/gkh258; PubMed=14960714 [NCBI, ExPASy, EBI, Israel, Japan]
Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.;
"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1.";
Nucleic Acids Res. 32:977-988(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017194; AAS40860.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_978252.1; -.
3D structure databases
ModBase Q73A47.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q73A47.
Genome annotation databases
GeneID 2747189; -.
GenomeReviews AE017194_GR; BCE_1936.
KEGG bca:BCE_1936; -.
NMPDR fig|222523.1.peg.1924; -.
TIGR BCE_1936; -.
Phylogenomic databases
HOGENOM Q73A47; -.
Other
ProtoNet Q73A47.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   335  335     Ketol-acid reductoisomerase 2. PRO_0000151273
ACT_SITE   106   106        Potential. 
Sequence information
Length: 335 AA [This is the length of the unprocessed precursor] Molecular weight: 36898 Da [This is the MW of the unprocessed precursor] CRC64: E3424127E43BDEE4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKTYYEKDAN VELLKGKTVA VIGYGSQGHA QAQNLRDSGV EVVVGVRPGK SFEVAKTDGF 

        70         80         90        100        110        120 
EVMSVSEAVR TAQVVQMLLP DEQQAHVYKA GVEENLREGQ MLLFSHGFNI HFGQINPPSY 

       130        140        150        160        170        180 
VDVAMVAPKS PGHLVRRVFQ EGNGVPALVA VHQDATGTAL HVALAYAKGV GCTRAGVIET 

       190        200        210        220        230        240 
TFQEETETDL FGEQTVLCGG VTALVKAGFE TLTEGGYRPE IAYFECLHEL KLIVDLMYEG 

       250        260        270        280        290        300 
GLTNMRHSIS DTAEFGDYVT GSRIVTDETK KEMKRVLTEI QQGEFAKKWI LENQAGRPTY 

       310        320        330 
NAMKKAEQNH QLEKVGAELR EMMSWIDAPK ELVKK 

Q73A47 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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