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UniProtKB/Swiss-Prot entry Q6P8J7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name KCRS_MOUSE
Primary accession number Q6P8J7
Secondary accession numbers None
Integrated into Swiss-Prot on June 21, 2005
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Creatine kinase, sarcomeric mitochondrial [Precursor]
Synonyms EC 2.7.3.2
S-MtCK
Gene name
Name: Ckmt2
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Heart, and Lung;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC061221; AAH61221.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_940807.1; -.
UniGene Mm.316438
3D structure databases
SMR Q6P8J7; 47-413.
ModBase Q6P8J7.
Organism-specific databases
MGI MGI:1923972; Ckmt2.
Gene expression databases
ArrayExpress Q6P8J7; -.
CleanEx MM_CKMT2; -.
GermOnline ENSMUSG00000021622; Mus musculus.
Ontologies
GO
GO:0004111; Molecular function: creatine kinase activity (traceable author statement from MGI).
GO:0006603; Biological process: phosphocreatine metabolic process (traceable author statement from MGI).
QuickGo view.
Family and domain databases
InterPro IPR000749; ATP-gua_Ptrans.
IPR014746; Gln_synth/guanido_kin_cat.
Graphical view of domain structure.
Gene3D G3DSA:1.10.135.10; ATP-gua_Ptrans; 1.
G3DSA:3.30.590.10; ATP-gua_Ptrans; 1.
PANTHER PTHR11547; ATP-gua_Ptrans; 1.
Pfam PF00217; ATP-gua_Ptrans; 1.
PF02807; ATP-gua_PtransN; 1.
Pfam graphical view of domain structure.
PROSITE PS00112; GUANIDO_KINASE; 1.
BLOCKS Q6P8J7.
Genome annotation databases
Ensembl ENSMUSG00000021622; Mus musculus. [Contig view]
GeneID 76722; -.
KEGG mmu:76722; -.
Phylogenomic databases
HOGENOM Q6P8J7; -.
HOVERGEN Q6P8J7; -.
Other
SOURCE Ckmt2; Mus musculus.
ProtoNet Q6P8J7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Kinase; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Transferase; Transit peptide.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
TRANSIT   1    39  39     Mitochondrion. 
CHAIN   40   419  380     Creatine kinase, sarcomeric mitochondrial. PRO_0000016595
NP_BIND   162   166  5     ATP (By similarity). 
NP_BIND   354   359  6     ATP (By similarity). 
REGION   40    64  25     Cardiolipin-binding (By similarity). 
ACT_SITE   317   317        By similarity. 
BINDING   225   225        ATP (By similarity). 
BINDING   326   326        ATP (By similarity). 
BINDING   369   369        ATP (By similarity). 
Sequence information
Length: 419 AA [This is the length of the unprocessed precursor] Molecular weight: 47473 Da [This is the MW of the unprocessed precursor] CRC64: E9083E4F689903EF [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MASAFSKLLT GRNASLLFTT LGTSALTTGY LLNRQKVSAD AREQHKLFPP SADYPDLRKH 

        70         80         90        100        110        120 
NNCMAECLTP TIYAKLRNKM TPSGYTLDQC IQTGVDNPGH PFIKTVGMVA GDEESYEVFA 

       130        140        150        160        170        180 
DLFDPVIKLR HNGYDPRVMK HPTDLDASKI THGQFDERYV LSSRVRTGRS IRGLSLPPAC 

       190        200        210        220        230        240 
SRAERREVEN VAITALEGLK GDLAGRYYKL SEMTEQDQQR LIDDHFLFDK PVSPLLTCAG 

       250        260        270        280        290        300 
MARDWPDARG IWHNYDKTFL IWINEEDHTR VISMEKGGNM KRVFERFCRG LKEVERLIQE 

       310        320        330        340        350        360 
RGWEFMWNER LGYILTCPSN LGTGLRAGVH VRIPKLSKDP RFSKILENLR LQKRGTGGVD 

       370        380        390        400        410 
TAAVADVYDI SNIDRIGRSE VELVQIVIDG VNYLVDCEKK LERGQDIKVP PPLPQFGRK
Q6P8J7 in FASTA format

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