NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-98 / CGA009;
DOI=10.1038/nbt923; PubMed=14704707 [NCBI, ExPASy, EBI, Israel, Japan]
Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S.;
"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris.";
Nat. Biotechnol. 22:55-61(2004).

Comments

FUNCTION: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase (By similarity).
CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
SUBCELLULAR LOCATION: Cytoplasm (Probable).
SIMILARITY: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BX572598; CAE27244.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_947148.1; -.

3D structure databases

ModBase

Q6N8V0.

Enzyme and pathway databases

BioCyc

RPAL258594:RPA1803-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003887;	Molecular function: DNA-directed DNA polymerase activity (inferred from electronic annotation from HAMAP).
GO:0045020;	Biological process: error-prone DNA repair (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01902; -; 1.
PBIL [Tree]

InterPro

IPR011708; DNA_pol3_alpha.
IPR004365; NA_bd_OB_tRNA-helicase.
IPR004013; PHP_C.
IPR003141; PHP_N.
IPR004805; PolC_alpha.
Graphical view of domain structure.

Pfam

PF07733; DNA_pol3_alpha; 1.
PF02811; PHP; 1.
PF01336; tRNA_anti; 1.
Pfam graphical view of domain structure.

SMART

SM00481; POLIIIAc; 1.
SMART graphical view of domain structure.

TIGRFAMs

TIGR00594; polc; 1.

BLOCKS

Q6N8V0.

Genome annotation databases

GeneID

2692528; -.

GenomeReviews

BX571963_GR; RPA1803.

KEGG

rpa:RPA1803; -.

NMPDR

fig|258594.1.peg.1792; -.

Phylogenomic databases

HOGENOM

Q6N8V0; -.

Genome annotation databases

CMR

Q6N8V0; RPA1803.

Other

ProtoNet

Q6N8V0.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 1195`	`1195`		`Error-prone DNA polymerase.`	`PRO_0000103398`

Sequence information

Length: 1195 AA [This is the length of the unprocessed precursor]

Molecular weight: 133397 Da [This is the MW of the unprocessed precursor]

CRC64: 1D1F8E9803B1E1D0 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSARYAEIGV TTNFSFLEGG SHPQDYVHEA SRLGLDAIGI ADRNTLAGVV RAFSEFDNEE 

        70         80         90        100        110        120 
LIHKPKLLIG TRLCFADGTP DLLAYPTDRA AYGRLCRLLS AGKLRAGKGE CHLTFADLEA 

       130        140        150        160        170        180 
FIHERSPSIH ELATVIHPPS ASINQPSASI HQFPTPSWPG LTRPSTPTSK VVLVSVDARV 

       190        200        210        220        230        240 
KPGHDGGKRV ADNSQILLVV MPSYRFQTKT IAIALERLTA LNADAVWLGL TPYYRGDDKR 

       250        260        270        280        290        300 
RLARLRRIAA VARVPCIATN DVLYHHPRRR ALQDVLTCVR EKTSIDKAGR RLEGNAERHL 

       310        320        330        340        350        360 
KPAAEMARLF RHDPEAIAET LRFADRISFT LDELKYHYPD EPVPPGKTAQ AHLQDLTEQG 

       370        380        390        400        410        420 
IKQYFPNGIS DRLRATIAKE LAIIERRGYA HYFLTVHDIV RYARSQDILC QGRGSAANSA 

       430        440        450        460        470        480 
VCYVLGITCV DPTEIDLLFE RFVSEERDEP PDIDVDFEHS RREEVMQYIY RRYGRHRAAI 

       490        500        510        520        530        540 
VATVIHYRPR SAIRDVGKAL GLSEDVTAAL ADTVWGSWGK GLNEMQVRQA GLDPHNPMIG 

       550        560        570        580        590        600 
RAVELATELI GFPRHLSQHV GGYVLTQDRL DSYVPIGNAA MADRTFIEWD KDDIDAVKMM 

       610        620        630        640        650        660 
KVDVLALGML TCIRKGFHLI AQHKGVRFQL SDIKSEDDNA VYKMLQRGES IGVFQVESRA 

       670        680        690        700        710        720 
QMNMLPRLKP RCFYDLVIEV AIVRPGPIQG DMVHPYLRRR NGQEPVVYPS PSGEAGDKNE 

       730        740        750        760        770        780 
LRQILGKTLG VPLFQEQAMR IAIEAAHFTP DEANQLRRAM ATFRNVGTIG KFEAKMIGNL 

       790        800        810        820        830        840 
VKRGYDATFA KNCFEQIKGF GSYGFPESHA ASFAKLVYVS AWMKCEHPDA FCCALLNSQP 

       850        860        870        880        890        900 
MGFYAPAQIV GDARSNGVEV RPVDVSFSEG QCTLEERCGR HHAVRLGFRM IDGFRWADPD 

       910        920        930        940        950        960 
EERVQLEAGE PPSDDWAARI VAARARGAFT SLEQFARITA LPKRALILLA DADAFRSLGL 

       970        980        990       1000       1010       1020 
DRRAALWAVR RLPDDVPLPL FEAASAREQE DERAAPLPAM PMAEHVVADY QTVRLSLKGH 

      1030       1040       1050       1060       1070       1080 
PMEFLRALFA AERVVTCREV SRSEQRASGC WLRCAGVVLV RQRPGSANGV IFMTIEDETG 

      1090       1100       1110       1120       1130       1140 
IANIVVWPAV MEKYRKEVMG ARLVLVEGKV QASAEGVVHL VAERLIDRSA EMGRLAEGLV 

      1150       1160       1170       1180       1190 
RPALPDGADL YEPLTSEKYN YEALNGDRRD TPDAPAQRHR HPRDVRILPP SRDFH

Q6N8V0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools