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UniProtKB/Swiss-Prot entry Q6IP76

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AKT2B_XENLA
Primary accession number Q6IP76
Secondary accession numbers None
Integrated into Swiss-Prot on February 21, 2006
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 38)
Name and origin of the protein
Protein name RAC-beta serine/threonine-protein kinase B
Synonyms EC 2.7.11.1
RAC-PK-beta-B
Protein kinase Akt-2-B
Protein kinase B, beta-B
PKB beta-B
Gene name
Name: akt2-B
From
Xenopus laevis (African clawed frog) [TaxID: 8355] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Spleen;
NIH - Xenopus Gene Collection (XGC) project;
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC072041; AAH72041.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_001085101.1; -.
UniGene Xl.62681
3D structure databases
HSSP P05132; 1ATP. [HSSP ENTRY / PDB]
SMR Q6IP76; 1-112.
ModBase Q6IP76.
Family and domain databases
InterPro IPR015744; Akt.
IPR001849; PH.
IPR011993; PH_type.
IPR000961; Pkinase_C.
IPR000719; Prot_kinase_core.
IPR017441; Protein_kinase_ATP_bd_CS.
IPR017442; Se/Thr_pkinase-rel.
IPR008271; Ser_thr_pkin_AS.
IPR002290; Ser_thr_pkinase.
Graphical view of domain structure.
Gene3D G3DSA:2.30.29.30; PH_type; 1.
PANTHER PTHR22985:SF69; Akt; 1.
Pfam PF00169; PH; 1.
PF00069; Pkinase; 1.
PF00433; Pkinase_C; 1.
Pfam graphical view of domain structure.
ProDom PD000001; Prot_kinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00233; PH; 1.
SM00133; S_TK_X; 1.
SM00220; S_TKc; 1.
SMART graphical view of domain structure.
PROSITE PS51285; AGC_KINASE_CTER; 1.
PS50003; PH_DOMAIN; 1.
PS00107; PROTEIN_KINASE_ATP; 1.
PS50011; PROTEIN_KINASE_DOM; 1.
PS00108; PROTEIN_KINASE_ST; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q6IP76.
Genome annotation databases
GeneID 432172; -.
KEGG xla:432172; -.
Phylogenomic databases
HOVERGEN Q6IP76; -.
Other
ProtoNet Q6IP76.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Kinase; Nucleotide-binding; Phosphoprotein; Serine/threonine-protein kinase; Transferase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   485  485     RAC-beta serine/threonine-protein kinase B. PRO_0000223509
DOMAIN   5   109  105     PH. 
DOMAIN   156   413  258     Protein kinase. 
DOMAIN   414   485  72     AGC-kinase C-terminal. 
NP_BIND   162   170  9     ATP (By similarity). 
ACT_SITE   279   279        Proton acceptor (By similarity). 
BINDING   185   185        ATP (By similarity). 
MOD_RES   313   313        Phosphothreonine (By similarity). 
MOD_RES   478   478        Phosphoserine (By similarity). 
Sequence information
Length: 485 AA [This is the length of the unprocessed precursor] Molecular weight: 56024 Da [This is the MW of the unprocessed precursor] CRC64: 27D584109098CC56 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNEVMVIKEG WLQKRGEYIK TWRPRYFLLK SDGSFIGYKE KPDSTEHSLL PPLNNFSVAE 

        70         80         90        100        110        120 
CQLMKTERPR PNTFVIRCLQ WTTVIERTFH VDTPEEREEW IIAIQTVANG LKNQVPEDEE 

       130        140        150        160        170        180 
EEAMEVKYGS PSDVSSAEQM DVAMSKGRPK VTMNDFDYLK LLGKGTFGKV ILVREKATGL 

       190        200        210        220        230        240 
YYAMKILRKE VIIAKDEVAH TLTESRVLQN TKHPFLTGLK YAFQTSDRLC FVMEYANGGE 

       250        260        270        280        290        300 
LFFHLSRERV FTEDRARFYG AEIVSALEYL HSRNVVYRDI KLENLMLDKD GHVKITDFGL 

       310        320        330        340        350        360 
CKEGITDGAT MRTFCGTPEY LAPEVLEDND YGRAVDWWGL GVVMYEMMCG RLPFYNQDHE 

       370        380        390        400        410        420 
RLFELILMEE TRFPRTLSPE AKSLLAGLLK KDPKQRLGGG PDDAQEVMSH GFFASINWQD 

       430        440        450        460        470        480 
VTERKLSPPF KPQVTSEIDT RYFDDEFTAQ SITLTPPDRY DNLDALESEQ RPHFPQFSYS 


SSIRE
Q6IP76 in FASTA format

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