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UniProtKB/Swiss-Prot entry Q6GG09


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name KPYK_STAAR
Primary accession number Q6GG09
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 25)
Name and origin of the protein
Protein name Pyruvate kinase
Synonyms PK
EC 2.7.1.40
Gene name
Name: pyk
OrderedLocusNames: SAR1776
From
Staphylococcus aureus (strain MRSA252) [TaxID: 282458] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0402521101; PubMed=15213324 [NCBI, ExPASy, EBI, Israel, Japan]
Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance.";
Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX571856; CAG40767.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_041163.1; -.
3D structure databases
ModBase Q6GG09.
Enzyme and pathway databases
BioCyc SAUR282458:SAR1776-MON; -.
Family and domain databases
InterPro IPR008279; PEP_mobile.
IPR001697; Pyr_Knase.
IPR015813; Pyrv/PenolPyrv_Kinase_cat.
IPR015794; Pyrv_Knase_a/b.
IPR015793; Pyrv_Knase_brl.
Graphical view of domain structure.
Gene3D G3DSA:3.50.30.10; PEP_mobile; 1.
G3DSA:3.20.20.60; Pyrv/PenolPyrv_Kinase_cat; 1.
G3DSA:3.40.1380.20; Pyrv_Knase_a/b; 1.
PANTHER PTHR11817; Pyruvate_kinase; 1.
Pfam PF00391; PEP-utilizers; 1.
PF00224; PK; 1.
PF02887; PK_C; 1.
Pfam graphical view of domain structure.
PRINTS PR01050; PYRUVTKNASE.
ProDom PD001009; Pyruvate_kinase; 2.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01064; pyruv_kin; 1.
PROSITE PS00110; PYRUVATE_KINASE; FALSE_NEG.
BLOCKS Q6GG09.
ProtoNet Q6GG09.
Genome annotation databases
GeneID 2861244; -.
GenomeReviews BX571856_GR; SAR1776.
KEGG sar:SAR1776; -.
Phylogenomic databases
HOGENOM Q6GG09; -.
Genome annotation databases
CMR Q6GG09; SAR1776.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Kinase; Magnesium; Metal-binding; Pyruvate; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   585  585     Pyruvate kinase. PRO_0000294130
ACT_SITE   219   219        By similarity. 
METAL   221   221        Magnesium (By similarity). 
METAL   242   242        Magnesium (By similarity). 
METAL   243   243        Magnesium (By similarity). 
Sequence information
Length: 585 AA [This is the length of the unprocessed precursor] Molecular weight: 63142 Da [This is the MW of the unprocessed precursor] CRC64: 87D790B356585362 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRKTKIVCTI GPASESEEMI EKLINAGMNV ARLNFSHGSH EEHKGRIDTI RKVAKRLDKI 

        70         80         90        100        110        120 
VAILLDTKGP EIRTHNMKDG IIELERGNEV IVSMNEVEGT PEKFSVTYEN LINDVQVGSY 

       130        140        150        160        170        180 
ILLDDGLIEL QVKDIDHAKK EVKCDILNSG ELKNKKGVNL PGVRVSLPGI TEKDAEDIRF 

       190        200        210        220        230        240 
GIKENVDFIA ASFVRRPSDV LEIREILEEQ KANISVFPKI ENQEGIDNIE EILEVSDGLM 

       250        260        270        280        290        300 
VARGDMGVEI PPEKVPMVQK DLIRQCNKLG KPVITATQML DSMQRNPRAT RAEASDVANA 

       310        320        330        340        350        360 
IYDGTDAVML SGETAAGLYP EEAVKTMRNI AVSAEAAQDY KKLLSDRTKL VETSLVNAIG 

       370        380        390        400        410        420 
ISVAHTALNL NVKAIVAATE SGSTARTISK YRPHSDIIAV TPSEETARQC SIVWGVQPVV 

       430        440        450        460        470        480 
KKGRKSTDAL LNNAVATAVE TGRVTNGDLI IITAGVPTGE TGTTNMMKIH LVGDEIANGQ 

       490        500        510        520        530        540 
GIGRGSVVGT TLVAETVKDL EGKDLSDKVI VTNSIDETFV PYVEKALGLI TEENGITSPS 

       550        560        570        580 
AIVGLEKGIP TVVGVEKAVK NISNNVLVTI DAAQGKIFEG YANVL 

Q6GG09 in FASTA format

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