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UniProtKB/Swiss-Prot entry Q6GDJ7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ALF1_STAAR
Primary accession number Q6GDJ7
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 2005
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 29)
Name and origin of the protein
Protein name Fructose-bisphosphate aldolase class 1
Synonyms EC 4.1.2.13
Fructose-biphosphate aldolase class I
FBP aldolase
Gene name
Name: fda
OrderedLocusNames: SAR2684
From
Staphylococcus aureus (strain MRSA252) [TaxID: 282458] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0402521101; PubMed=15213324 [NCBI, ExPASy, EBI, Israel, Japan]
Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance.";
Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX571856; CAG41661.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_042026.1; -.
3D structure databases
ModBase Q6GDJ7.
Enzyme and pathway databases
BioCyc SAUR282458:SAR2684-MON; -.
Ontologies
GO
GO:0004332; Molecular function: fructose-bisphosphate aldolase activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00729; -; 1.
PBIL [Tree]
InterPro IPR000741; Aldolase_I.
IPR013785; Aldolase_TIM.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
PANTHER PTHR11627; Aldolase_I; 1.
Pfam PF00274; Glycolytic; 1.
Pfam graphical view of domain structure.
ProDom PD001128; Aldolase_I; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00158; ALDOLASE_CLASS_I; FALSE_NEG.
BLOCKS Q6GDJ7.
ProtoNet Q6GDJ7.
Genome annotation databases
GeneID 2860659; -.
GenomeReviews BX571856_GR; SAR2684.
KEGG sar:SAR2684; -.
Phylogenomic databases
HOGENOM Q6GDJ7; -.
Genome annotation databases
CMR Q6GDJ7; SAR2684.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Lyase; Schiff base.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   296  295     Fructose-bisphosphate aldolase class 1. PRO_0000216906
ACT_SITE   175   175        Proton acceptor (By similarity). 
ACT_SITE   212   212        Schiff-base intermediate with dihydroxyacetone-P (By similarity). 
Sequence information
Length: 296 AA [This is the length of the unprocessed precursor] Molecular weight: 32913 Da [This is the MW of the unprocessed precursor] CRC64: CB1EF5FA63576D51 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNKEQLEKMK NGKGFIAALD QSGGSTPKAL KEYGVNEDQY SNEDEMFQLV HDMRTRVVTS 

        70         80         90        100        110        120 
PSFSPDKILG AILFEQTMDR EVEGKYTADY LADKGVVPFL KVDKGLAEEQ NGVQLMKPID 

       130        140        150        160        170        180 
NLDSLLDRAN ERHIFGTKMR SNILELNEQG IKDVVEQQFE VAKQIIAKGL VPIIEPEVNI 

       190        200        210        220        230        240 
NAKDKAEIEK VLKAELKKGL DSLNADQLVM LKLTIPTEAN LYKDLAEHPN VVRIVVLSGG 

       250        260        270        280        290 
YSREKANELL KDNAELIASF SRALASDLRA GQSKEEFDKA LGDAVESIYD ASVNKN 

Q6GDJ7 in FASTA format

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