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UniProtKB/Swiss-Prot entry Q6G711

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FDHL_STAAS
Primary accession number Q6G711
Secondary accession numbers None
Integrated into Swiss-Prot on September 11, 2007
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 33)
Name and origin of the protein
Protein name Putative formate dehydrogenase SAS2201
Synonym EC 1.2.1.2
Gene name
OrderedLocusNames: SAS2201
From
Staphylococcus aureus (strain MSSA476) [TaxID: 282459] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0402521101; PubMed=15213324 [NCBI, ExPASy, EBI, Israel, Japan]
Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J., Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A., Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C., Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z., Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N., Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M., Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
"Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance.";
Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX571857; CAG44012.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_044313.1; -.
3D structure databases
ModBase Q6G711.
Enzyme and pathway databases
BioCyc SAUR282459:SAS2201-MON; -.
Ontologies
GO
GO:0051537; Molecular function: 2 iron, 2 sulfur cluster binding (inferred from electronic annotation from UniProtKB-KW).
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from UniProtKB-KW).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001450; 4Fe4S_Fe_S_bd.
IPR009010; Asp_de-COase-like_fold.
IPR001041; Ferredoxin.
IPR006478; Formate_DHase_asu.
IPR006656; Mopterin_OxRdtase.
IPR006963; Mopterin_OxRdtase_Fe4S4.
IPR006655; Mopterin_OxRdtase_prok_CS.
IPR006657; MPT_dinuc_bd.
Graphical view of domain structure.
Gene3D G3DSA:2.40.40.20; Asp_decarboxylase-like_fold; 1.
Pfam PF00111; Fer2; 1.
PF00037; Fer4; 2.
PF04879; Molybdop_Fe4S4; 1.
PF00384; Molybdopterin; 1.
PF01568; Molydop_binding; 1.
Pfam graphical view of domain structure.
PRINTS PR00353; 4FE4SFRDOXIN.
TIGRFAMs TIGR01591; Fdh-alpha; 1.
PROSITE PS51085; 2FE2S_FER_2; 1.
PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 2.
PS00551; MOLYBDOPTERIN_PROK_1; 1.
PS00490; MOLYBDOPTERIN_PROK_2; FALSE_NEG.
PS00932; MOLYBDOPTERIN_PROK_3; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q6G711.
ProtoNet Q6G711.
Genome annotation databases
GeneID 2863871; -.
GenomeReviews BX571857_GR; SAS2201.
KEGG sas:SAS2201; -.
Phylogenomic databases
HOGENOM Q6G711; -.
Genome annotation databases
CMR Q6G711; SAS2201.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding; Molybdenum; NAD; Oxidoreductase; Repeat.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   984  984     Putative formate dehydrogenase SAS2201. PRO_0000304131
DOMAIN   3    79  77     2Fe-2S ferredoxin-type. 
DOMAIN   138   165  28     4Fe-4S ferredoxin-type 1. 
DOMAIN   181   211  31     4Fe-4S ferredoxin-type 2. 
REGION   252   984  733     Formate dehydrogenase. 
METAL   37    37        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   48    48        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   51    51        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   63    63        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   95    95        Iron-sulfur 2 (4Fe-4S); via tele nitrogen (By similarity). 
METAL   99    99        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   102   102        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   109   109        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   147   147        Iron-sulfur 3 (4Fe-4S) (By similarity). 
METAL   150   150        Iron-sulfur 3 (4Fe-4S) (By similarity). 
METAL   153   153        Iron-sulfur 3 (4Fe-4S) (By similarity). 
METAL   157   157        Iron-sulfur 4 (4Fe-4S) (By similarity). 
METAL   190   190        Iron-sulfur 4 (4Fe-4S) (By similarity). 
METAL   193   193        Iron-sulfur 4 (4Fe-4S) (By similarity). 
METAL   196   196        Iron-sulfur 4 (4Fe-4S) (By similarity). 
METAL   200   200        Iron-sulfur 3 (4Fe-4S) (By similarity). 
METAL   264   264        Iron-sulfur 5 (4Fe-4S) (By similarity). 
METAL   267   267        Iron-sulfur 5 (4Fe-4S) (By similarity). 
METAL   271   271        Iron-sulfur 5 (4Fe-4S) (By similarity). 
METAL   299   299        Iron-sulfur 5 (4Fe-4S) (By similarity). 
Sequence information
Length: 984 AA [This is the length of the unprocessed precursor] Molecular weight: 111295 Da [This is the MW of the unprocessed precursor] CRC64: 79140674B6A0C1D3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQEHLVVTLD GKDYLVEPGT NLLEFIKSQD TFVPSICYNE SMGPIQTCDT CTVEIDGKIE 

        70         80         90        100        110        120 
RSCSTVIDRP MTVNTVNNDV KDAQKEALDR ILEKHMLYCT VCDYNNGDCE IHNTMDAWGL 

       130        140        150        160        170        180 
QHQTYEYKEK PYEKDYGPFY RYDPNQCILC GRCVEACQDI EVNETIRIDW DREHPRVIWD 

       190        200        210        220        230        240 
NDVPINESSC VSCGQCATVC PCNAMMEVNM EGNAGYMTDT EPGSLAAMID LTKKAEPGYG 

       250        260        270        280        290        300 
PLFAISDSEA EMRKERIKKT KTVCTYCGVG CSFEVWTKDR EILKVQPSHD SPANKIATCV 

       310        320        330        340        350        360 
KGKFSWGHIN SDQRLTKPLV RKNGEFHEVE WDEALNVIAD NFTSIKEKYG PDALSFISSS 

       370        380        390        400        410        420 
KATNEESYLM QKLARQVIGT NNVDNCSRYC QAPATKGLFR TVGHGGDSGS IEDLEKAAMS 

       430        440        450        460        470        480 
VLIGTNTAEA HPVIASRMKR AQKLFGQKIH VFDIRKHEMA ERADRFYQPK PGTDLAWLSA 

       490        500        510        520        530        540 
VTKYIIDHDL HDKAFIDEWV DDFDEYYKSL ETFTMAFAEE ATGIPESELI KFAEECAKAE 

       550        560        570        580        590        600 
SVVICWAMGI TQQDIGSDSS TAISNLLLVT GNYRRPGTGA YPLRGHNNVQ GCSDMGSMPD 

       610        620        630        640        650        660 
KITGYQSIEA DDIRAKFEKE YGVKLNPKAG KDNHEMVEGI HDGEVHSLYL YGEDTGIVDS 

       670        680        690        700        710        720 
NINFVQAAFE KLDFMVVQDE FLTFTATYAD VVLPASPSLE KDGTFTNTER RIQRLYQALE 

       730        740        750        760        770        780 
PLGDSKPDWK IFQAIANRLG FDWNYKHPSE IMDEVARLTP LYAGVSYDRL EGFNSLQWPV 

       790        800        810        820        830        840 
QPDGTDEPIL YLEGFNFDNG KAKLFPLSFD NYFKQDEIYD IHVNNGRLLE HFHEGNMTYQ 

       850        860        870        880        890        900 
TPMIKYKVPR AFVEISPELA EDRGIHEGAE VKLISETGEA VLQVHVTDRV KGKEIYIPLN 

       910        920        930        940        950        960 
NDAMENGDLG AINLLTNSDV DQYTDTPSYK RTSCRLEVIT KRGKSPLNPN NFRVNKKRHP 

       970        980 
QYSVQVQKKW ERSDYVFPGN QVDK
Q6G711 in FASTA format

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