ID   NTPA_BARHE              Reviewed;         215 AA.
AC   Q6G565;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   22-JUL-2008, entry version 24.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=NTPase;
GN   OrderedLocusNames=BH00540;
OS   Bartonella henselae (Rochalimaea henselae).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bartonellaceae; Bartonella.
OX   NCBI_TaxID=38323;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49882 / Houston 1;
RX   PubMed=15210978; DOI=10.1073/pnas.0305659101;
RA   Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H.,
RA   Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M.,
RA   La Scola B., Holmberg M., Andersson S.G.E.;
RT   "The louse-borne human pathogen Bartonella quintana is a genomic
RT   derivative of the zoonotic agent Bartonella henselae.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; BX897699; CAF26870.1; -; Genomic_DNA.
DR   RefSeq; YP_032919.1; -.
DR   GeneID; 2865975; -.
DR   GenomeReviews; BX897699_GR; BH00540.
DR   KEGG; bhe:BH00540; -.
DR   NMPDR; fig|283166.1.peg.47; -.
DR   HOGENOM; Q6G565; -.
DR   BioCyc; BHEN283166:BH00540-MON; -.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p_like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    215       Nucleoside-triphosphatase.
FT                                /FTId=PRO_0000178131.
SQ   SEQUENCE   215 AA;  23662 MW;  81412B2F37053261 CRC64;
     MRSIANKKLV IATHNIGKLQ EITTLVAPFG LTIQSAKELG LPEPKETGTT FEENAYIKAF
     AAAKNTGLPA LSDDSGLEVD ALNGAPGVYT ADLALQSDGT RDFLKAMQKI EEKLQKIGAH
     KKSQRKCRFI SVICIAWPDA HADYFHGRVE GSFIWPPRGD KGFGFDPVFL PDGYKNTFGE
     MTTEQKHGWK LNDQTPLSHR ACAFKLLAEN LLKLS
//