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UniProtKB/Swiss-Prot entry Q6FZ98


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_BARQU
Primary accession number Q6FZ98
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 32)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: BQ08540
From
Bartonella quintana (Rochalimaea quintana) [TaxID: 803] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bartonellaceae; Bartonella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Toulouse;
DOI=10.1073/pnas.0305659101; PubMed=15210978 [NCBI, ExPASy, EBI, Israel, Japan]
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.;
"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae.";
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX897700; CAF26333.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_032470.1; -.
3D structure databases
ModBase Q6FZ98.
Enzyme and pathway databases
BioCyc BQUI283165:BQ08540-MON; -.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q6FZ98.
Genome annotation databases
GeneID 2866764; -.
GenomeReviews BX897700_GR; BQ08540.
KEGG bqu:BQ08540; -.
NMPDR fig|283165.1.peg.740; -.
Phylogenomic databases
HOGENOM Q6FZ98; -.
Genome annotation databases
CMR Q6FZ98; BQ08540.
Other
ProtoNet Q6FZ98.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   339  339     Ketol-acid reductoisomerase. PRO_0000226162
ACT_SITE   108   108        Potential. 
Sequence information
Length: 339 AA [This is the length of the unprocessed precursor] Molecular weight: 37325 Da [This is the MW of the unprocessed precursor] CRC64: E5BA16F0BCC8E3BD [This is a checksum on the sequence]
        10         20         30         40         50         60 
MHVYYDHDAN VNLIKGKKVA IVGYGSQGHA HALNLKDSGV QDVRIALHSR SATAKKAIAD 

        70         80         90        100        110        120 
GFEVVRVAEA AKWADLIMMA TPDELQADIY KEHMHDDLRD GAVIAFAHGL SIHFGLIEPK 

       130        140        150        160        170        180 
KTVDVVMIAP KGPGHKVRNE YQRGCGVPCL IAVAQDVSGH AHDIALSYAC GIGGGRAGVM 

       190        200        210        220        230        240 
ETTFKEECET DLFGEQAVLC GGLVELIRAG YETLTEAGYA PEMAYFECLH EVKLIVDLLY 

       250        260        270        280        290        300 
EGGIANMNYS ISNTAEWGEY ISGPRVITDK TKAEMRRILK DIQTGKFTSN WIQECKAGAI 

       310        320        330 
HFKSMRRLND SHPIEEVGKK LRSMMPWIKS NALVDKKRN 

Q6FZ98 in FASTA format

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