ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q6FZ74

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name DDL_BARQU
Primary accession number Q6FZ74
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 38)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase
Synonyms EC 6.3.2.4
D-alanylalanine synthetase
D-Ala-D-Ala ligase
Gene name
Name: ddl
OrderedLocusNames: BQ08830
From
Bartonella quintana (Rochalimaea quintana) [TaxID: 803] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bartonellaceae; Bartonella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Toulouse;
DOI=10.1073/pnas.0305659101; PubMed=15210978 [NCBI, ExPASy, EBI, Israel, Japan]
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.;
"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae.";
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX897700; CAF26362.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_032495.1; -.
3D structure databases
ModBase Q6FZ74.
Enzyme and pathway databases
BioCyc BQUI283165:BQ08830-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q6FZ74.
Genome annotation databases
GeneID 2867175; -.
GenomeReviews BX897700_GR; BQ08830.
KEGG bqu:BQ08830; -.
NMPDR fig|283165.1.peg.765; -.
Phylogenomic databases
HOGENOM Q6FZ74; -.
Genome annotation databases
CMR Q6FZ74; BQ08830.
Other
ProtoNet Q6FZ74.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   306  306     D-alanine--D-alanine ligase. PRO_1000030430
DOMAIN   102   300  199     ATP-grasp. 
NP_BIND   128   183  56     ATP (By similarity). 
METAL   253   253        Magnesium or manganese 1 (By similarity). 
METAL   267   267        Magnesium or manganese 1 (By similarity). 
METAL   267   267        Magnesium or manganese 2 (By similarity). 
METAL   269   269        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 306 AA [This is the length of the unprocessed precursor] Molecular weight: 33288 Da [This is the MW of the unprocessed precursor] CRC64: 1ACFFD24DB7374BD [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKGEHVAVLM GGGSSERSVS LSSGTACADI LEARGYRVSR VDVDSHIASV LERLQPDVAF 

        70         80         90        100        110        120 
NALHGPFGED GCIQGVLEYL KIPYTHSGVM ASALAMDKGR AKIVVASVGV SVAPSCIMSR 

       130        140        150        160        170        180 
FAVGREHPME PPYVIKPLCE GSSFGVVIVK ENESAPPRNV VGAEWVYADE VIVEKYIPGR 

       190        200        210        220        230        240 
EFTCAVLGNE ALDVCEIFPD KHFQFYNYDS KYKSGGSLHI CPAQLSPNIY QNVQRMSLAA 

       250        260        270        280        290        300 
HQAIGCRGVS RSDFRFNEET GELVWLEINT QPGMTPTSLF PDIAKASGRT YGDIVQWMVE 


DASCMR
Q6FZ74 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!