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UniProtKB/Swiss-Prot entry Q6FFL8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAO1_ACIAD
Primary accession number Q6FFL8
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 29)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: ACIAD0166
From
Acinetobacter sp. (strain ADP1) [TaxID: 62977] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Moraxellaceae; Acinetobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/nar/gkh910; PubMed=15514110 [NCBI, ExPASy, EBI, Israel, Japan]
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium.";
Nucleic Acids Res. 32:5766-5779(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR543861; CAG67139.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_044961.1; -.
3D structure databases
ModBase Q6FFL8.
Enzyme and pathway databases
BioCyc ASP62977:ACIAD0166-MON; -.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q6FFL8.
Genome annotation databases
GeneID 2879295; -.
GenomeReviews CR543861_GR; ACIAD0166.
KEGG aci:ACIAD0166; -.
NMPDR fig|62977.3.peg.256; -.
Phylogenomic databases
HOGENOM Q6FFL8; -.
Genome annotation databases
CMR Q6FFL8; ACIAD0166.
Other
ProtoNet Q6FFL8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   566  566     NAD-dependent malic enzyme. PRO_0000160212
ACT_SITE   105   105        Proton donor (By similarity). 
ACT_SITE   176   176        Proton acceptor (By similarity). 
METAL   247   247        Divalent metal cation (By similarity). 
METAL   248   248        Divalent metal cation (By similarity). 
METAL   271   271        Divalent metal cation (By similarity). 
BINDING   158   158        NAD (By similarity). 
BINDING   271   271        NAD (By similarity). 
BINDING   419   419        NAD (By similarity). 
SITE   271   271  1     Important for activity (By similarity). 
Sequence information
Length: 566 AA [This is the length of the unprocessed precursor] Molecular weight: 62969 Da [This is the MW of the unprocessed precursor] CRC64: 2122BE03FE5FFC65 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTAETNTNKH PLYIPYAGYT LLELPLLNKG SAFTQEERSH FNLHGLIPHV IETIEEQSQR 

        70         80         90        100        110        120 
SYQQYGAFND DINKHIYLRN IQDTNETLFY RLINDHLEEM MPIIYTPTVG EACQRFSDIY 

       130        140        150        160        170        180 
RRHRGIFISY PDREHIDDIL QNVSKRNVKV IVITDGERIL GLGDQGIGGM GIPIGKLSLY 

       190        200        210        220        230        240 
TACGGISPAY TLPITIDVGT NNQQLLNDPI YMGWRQPRIS GDEYYEFIDQ VLTGIRRRWP 

       250        260        270        280        290        300 
HALIQFEDFA QKNAMPLLTK YRDKFCCFND DIQGTAAVSV GSLIAASRAA GKQLKDQTIT 

       310        320        330        340        350        360 
FLGAGSAGCG IAEQIVAQMV AEGLTDAQAR ARVYMVDRFG LITENQPNLL DFQRKLAQKA 

       370        380        390        400        410        420 
EVVSDWGNVE EVISLLDVVK NAKPTVLIGV SGQPGLFTEE VIRTLAENCE RPIVMPLSNP 

       430        440        450        460        470        480 
TSRVEALPSD VIQWTNGRAL IATGSPFAPV NYQGKLYNIS QCNNSYIFPG IGLGVIASGA 

       490        500        510        520        530        540 
KRVTDNMLMA SSNALADCSP LLQNPNADLL PAIADIQDVS KRIAFKVAKA AIEDGVALNM 

       550        560 
SDEVLLQNIE KEFWKPKYRG YKRVPF
Q6FFL8 in FASTA format

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