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UniProtKB/Swiss-Prot entry Q6D698

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRC_ERWCT
Primary accession number Q6D698
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 30)
Name and origin of the protein
Protein name Dihydroorotase
Synonyms DHOase
EC 3.5.2.3
Gene name
Name: pyrC
OrderedLocusNames: ECA1787
From
Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) [TaxID: 29471] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Pectobacterium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SCRI 1043 / ATCC BAA-672;
DOI=10.1073/pnas.0402424101; PubMed=15263089 [NCBI, ExPASy, EBI, Israel, Japan]
Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J., Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K., Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J., Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H., Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S., Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
"Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors.";
Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX950851; CAG74692.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_049887.1; -.
3D structure databases
SMR Q6D698; 7-347.
ModBase Q6D698.
Enzyme and pathway databases
BioCyc ECAR218491:ECA1787-MON; -.
Ontologies
GO
GO:0004151; Molecular function: dihydroorotase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00219; -; 1.
PBIL [Tree]
InterPro IPR006680; Amidohydro_1.
IPR004721; DHOdimr.
IPR002195; Dihydroorotase_CS.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001237; DHOdimr; 1.
TIGRFAMs TIGR00856; pyrC_dimer; 1.
PROSITE PS00482; DIHYDROOROTASE_1; FALSE_NEG.
PS00483; DIHYDROOROTASE_2; 1.
BLOCKS Q6D698.
Genome annotation databases
GeneID 2882669; -.
GenomeReviews BX950851_GR; ECA1787.
KEGG eca:ECA1787; -.
NMPDR fig|218491.3.peg.257; -.
Phylogenomic databases
HOGENOM Q6D698; -.
Genome annotation databases
CMR Q6D698; ECA1787.
Other
ProtoNet Q6D698.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   347  347     Dihydroorotase. PRO_1000024013
METAL   17    17        Zinc 1 (By similarity). 
METAL   19    19        Zinc 1 (By similarity). 
METAL   103   103        Zinc 1 (via carbamate group) (By similarity). 
METAL   103   103        Zinc 2 (via carbamate group) (By similarity). 
METAL   140   140        Zinc 2 (By similarity). 
METAL   178   178        Zinc 2 (By similarity). 
METAL   251   251        Zinc 1 (By similarity). 
MOD_RES   103   103        N6-carboxylysine (By similarity). 
Sequence information
Length: 347 AA [This is the length of the unprocessed precursor] Molecular weight: 38615 Da [This is the MW of the unprocessed precursor] CRC64: 15507D1F7ABD903E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTAQHTILKI RRPDDWHIHL RDDRMLETVL PYTSRFFGRA IVMPNLTPPI TSVASAIAYR 

        70         80         90        100        110        120 
QRILAAVPQG DNFHPLMTCY LTDTLDANEI VSGFEQGVFT AAKLYPANAT TNSSHGVTSV 

       130        140        150        160        170        180 
ATISGILEKM QKIGMPLLIH GEVTDPAIDI FDREARFIET ILEPLRQDFP ELKVVLEHIT 

       190        200        210        220        230        240 
TKEAAEYVIA GNDYLAATIT PQHLMFNRNH MLVGGIRTHL YCLPILKRNT HQQALREAVA 

       250        260        270        280        290        300 
SGCDRLFLGT DSAPHAKHRK ESSCGCAGVF NAQAALSTYA TVFEEMNALD KLEAFCSLNG 

       310        320        330        340 
PRFYGLPVND SWIELHREAV TFPEEIALGD ESLIPFLAGQ SLNWSVR
Q6D698 in FASTA format

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