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UniProtKB/Swiss-Prot entry Q6CDR5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HPPD_YARLI
Primary accession number Q6CDR5
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 28)
Name and origin of the protein
Protein name 4-hydroxyphenylpyruvate dioxygenase
Synonyms HPPDase
4HPPD
HPD
EC 1.13.11.27
Gene name
OrderedLocusNames: YALI0B21846g
From
Yarrowia lipolytica (Candida lipolytica) [TaxID: 4952] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CLIB 122 / E 150;
DOI=10.1038/nature02579; PubMed=15229592 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR382128; CAG83450.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_501197.1; -.
3D structure databases
ModBase Q6CDR5.
Family and domain databases
InterPro IPR005956; 4OHPhenylPyrv_dOase.
IPR004360; Glyas_bleo-R_dOase.
Graphical view of domain structure.
PANTHER PTHR11959; HPP_dOase; 1.
Pfam PF00903; Glyoxalase; 2.
Pfam graphical view of domain structure.
PIRSF PIRSF009283; HPP_dOase; 1.
TIGRFAMs TIGR01263; 4HPPD; 1.
BLOCKS Q6CDR5.
Genome annotation databases
GeneID 2907146; -.
KEGG yli:YALI0B21846g; -.
Phylogenomic databases
HOGENOM Q6CDR5; -.
Other
ProtoNet Q6CDR5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   394  394     4-hydroxyphenylpyruvate dioxygenase. PRO_0000088407
METAL   196   196        Iron (By similarity). 
METAL   279   279        Iron (By similarity). 
METAL   362   362        Iron (By similarity). 
Sequence information
Length: 394 AA [This is the length of the unprocessed precursor] Molecular weight: 44190 Da [This is the MW of the unprocessed precursor] CRC64: 9588F1E0E3F7B95E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSPSVEVTPA HTPTSYEVTN SLDSYRGYDH VHWYVGNAKQ AASFYITRMG FSPIAYKGLE 

        70         80         90        100        110        120 
TGSRDVTTHV VGNGQVRFAF SSALRTGEPQ ADEIHAHLVK HGDAVKDVAF EVDNVEQLFS 

       130        140        150        160        170        180 
AAVKKGVRVI SEPKVLKDAH GSVTYAVIST YGDTTHTLIE RGSYEGAFLP GFVDTSANKD 

       190        200        210        220        230        240 
PIAAFLPNIE LMHIDHCVGN QDWNEMDNAC KYYEETLGFH RFWSVDDKDI CTEFSALKSV 

       250        260        270        280        290        300 
VMASPNEKIK MPVNEPAVGK KKSQIEEYID FYDGPGIQHI ALRTDCILDT VRDLRARGVE 

       310        320        330        340        350        360 
FISVPGSYYE NMKERLAKSS LKLEEKFEDI QALNILIDFD EGGYLLQLFT KPLMDRPTVF 

       370        380        390 
IEIIQRRNFE GFGAGNFKSL FEAIEREQAK RGNL 

Q6CDR5 in FASTA format

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