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UniProtKB/Swiss-Prot entry Q6AF87


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRC_LEIXX
Primary accession number Q6AF87
Secondary accession numbers None
Integrated into Swiss-Prot on August 2, 2005
Sequence was last modified on September 13, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 28)
Name and origin of the protein
Protein name Dihydroorotase
Synonyms DHOase
EC 3.5.2.3
Gene name
Name: pyrC
OrderedLocusNames: Lxx11070
From
Leifsonia xyli subsp. xyli [TaxID: 59736] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Micrococcineae; Microbacteriaceae; Leifsonia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CTCB07;
PubMed=15305603 [NCBI, ExPASy, EBI, Israel, Japan]
Monteiro-Vitorello C.B., Camargo L.E.A., Van Sluys M.A., Kitajima J.P., Truffi D., do Amaral A.M., Harakava R., de Oliveira J.C.F., Wood D., de Oliveira M.C., Miyaki C.Y., Takita M.A., da Silva A.C.R., Furlan L.R., Carraro D.M., Camarotte G., Almeida N.F. Jr., Carrer H., Coutinho L.L., El-Dorry H.A., Ferro M.I.T., Gagliardi P.R., Giglioti E., Goldman M.H.S., Goldman G.H., Kimura E.T., Ferro E.S., Kuramae E.E., Lemos E.G.M., Lemos M.V.F., Mauro S.M.Z., Machado M.A., Marino C.L., Menck C.F., Nunes L.R., Oliveira R.C., Pereira G.G., Siqueira W., de Souza A.A., Tsai S.M., Zanca A.S., Simpson A.J.G., Brumbley S.M., Setubal J.C.;
"The genome sequence of the Gram-positive sugarcane pathogen Leifsonia xyli subsp. xyli.";
Mol. Plant Microbe Interact. 17:827-836(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016822; AAT88958.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_062063.1; -.
3D structure databases
ModBase Q6AF87.
Enzyme and pathway databases
BioCyc LXYL281090:LXX11070-MON; -.
Ontologies
GO
GO:0004151; Molecular function: dihydroorotase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00220; -; 1.
PBIL [Tree]
InterPro IPR006680; Amidohydro_1.
IPR004722; DHOmult.
IPR002195; Dihydroorotase_CS.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00857; pyrC_multi; 1.
PROSITE PS00482; DIHYDROOROTASE_1; FALSE_NEG.
PS00483; DIHYDROOROTASE_2; 1.
BLOCKS Q6AF87.
Genome annotation databases
GeneID 2940482; -.
GenomeReviews AE016822_GR; Lxx11070.
KEGG lxx:Lxx11070; -.
NMPDR fig|281090.3.peg.477; -.
Phylogenomic databases
HOGENOM Q6AF87; -.
Genome annotation databases
CMR Q6AF87; Lxx11070.
Other
ProtoNet Q6AF87.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   438  438     Dihydroorotase. PRO_0000147238
METAL   58    58        Zinc 1 (By similarity). 
METAL   60    60        Zinc 1 (By similarity). 
METAL   179   179        Zinc 2 (By similarity). 
METAL   232   232        Zinc 2 (By similarity). 
METAL   305   305        Zinc 1 (By similarity). 
Sequence information
Length: 438 AA [This is the length of the unprocessed precursor] Molecular weight: 45446 Da [This is the MW of the unprocessed precursor] CRC64: A334453B012DDCA0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSDETFVITG AMLADGSRTD LLLAGGRIQE TGVRLSAAGA TVVDADGLLA LPGLVDLHTH 

        70         80         90        100        110        120 
LREPGYEQSE TVLTGTRAAA AGGFTEVFAM ANTSPVADTA GVVEQVLSLG EAAGYATVRP 

       130        140        150        160        170        180 
IGAVTVGLEG ERLAELGAMA DSRARVRVFS DDGKCVSDPL LMRRALEYVK AFDGVIAQHA 

       190        200        210        220        230        240 
QEPRITAGAQ MNEGALSGEL GLAGWPAVAE ESIIARDVLL AEHVGSRLHV CHVSTAGSVD 

       250        260        270        280        290        300 
VIRWAKARGI DVTAEVTPHH LLLTEELVSG YDARYKVNPP LRRSEDVEAL RAGLADGTID 

       310        320        330        340        350        360 
IVATDHAPHP VEAKDCEWDA AAFGMVGLES ALSVVQSSVV DTGMLGWADI ARVLSATPAR 

       370        380        390        400        410        420 
IGRLAGHGTP VEAGAPAELF LYDPAAAREF STGELAGKGV NSPYLSMTLS GRVVATFHRG 

       430 
YATVLDGAVL ESVGGARG 

Q6AF87 in FASTA format

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