NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=YCH46;
DOI=10.1073/pnas.0404172101; PubMed=15466707 [NCBI, ExPASy, EBI, Israel, Japan]
Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.;
"Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation.";
Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004).

Comments

FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions (By similarity).
CATALYTIC ACTIVITY: NTP + H₂O = NDP + phosphate.
COFACTOR: Divalent cations (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the HAM1 NTPase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP006841; BAD51325.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_101859.1; -.

3D structure databases

ModBase

Q64MG2.

Enzyme and pathway databases

BioCyc

BFRA295405:BF4588-MON; -.

Ontologies

GO:0017111;	Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01405; -; 1.
PBIL [Tree]

InterPro

IPR002637; Ham1p_like.
Graphical view of domain structure.

PANTHER

PTHR11067; Ham1p_like; 1.

Pfam

PF01725; Ham1p_like; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00042; Ham1p_like; 1.

BLOCKS

Q64MG2.

Genome annotation databases

3085664; -.

AP006841_GR; BF4588.

bfr:BF4588; -.

fig|295405.3.peg.4576; -.

Phylogenomic databases

HOGENOM

Q64MG2; -.

Genome annotation databases

CMR

Q64MG2; BF4588.

Other

ProtoNet

Q64MG2.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 194`	`194`		`Nucleoside-triphosphatase.`	`PRO_0000178123`

Sequence information

Length: 194 AA [This is the length of the unprocessed precursor]

Molecular weight: 21620 Da [This is the MW of the unprocessed precursor]

CRC64: B7DC34C6EDC4FA40 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKRKLVFATN NAHKLEEVSA ILGDKVELLS LNDINCHTDI PETAETLEGN AYLKSSFIYR 

        70         80         90        100        110        120 
NYGLNCFADD TGLEVESLGG APGVYSARYA GGEGHNAEAN MLKLLHELEG KDNRRAQFRT 

       130        140        150        160        170        180 
AISLILDEKE YLFEGIIKGE IIKEKRGDSG FGYDPVFVPE GYDRTFAELG NEIKNQISHR 

       190 
ALAVNKLCEF LRSI

Q64MG2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools