[1]	NUCLEOTIDE SEQUENCE. DOI=10.1007/BF00360561; PubMed=8111122 [NCBI, ExPASy, EBI, Israel, Japan] Brown K.A., Sutcliffe M.J., Steele K., Brown S.D.; "Sequencing of the olfactory marker protein gene in normal and shaker-1 mutant mice."; Mamm. Genome 5:11-14(1994).
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=129; DOI=10.1006/geno.1994.1200; PubMed=8034318 [NCBI, ExPASy, EBI, Israel, Japan] Buiakova O.I., Rama Krishna N.S., Getchell T.V., Margolis F.L.; "Human and rodent OMP genes: conservation of structural and regulatory motifs and cellular localization."; Genomics 20:452-462(1994).
[3]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. TISSUE=Olfactory epithelium; DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan] The MGC Project Team; "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."; Genome Res. 14:2121-2127(2004).
[4]	INTERACTION WITH BEX1 AND BEX2. PubMed=12911636 [NCBI, ExPASy, EBI, Israel, Japan] Behrens M., Margolis J.W., Margolis F.L.; "Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners."; J. Neurochem. 86:1289-1296(2003).
[5]	INTERACTION WITH BEX1 AND BEX2. DOI=10.1111/j.1471-4159.2004.02463.x; PubMed=15198671 [NCBI, ExPASy, EBI, Israel, Japan] Koo J.H., Gill S., Pannell L.K., Menco B.P.M., Margolis J.W., Margolis F.L.; "The interaction of Bex and OMP reveals a dimer of OMP with a short half-life."; J. Neurochem. 90:102-116(2004).
[6]	X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS). DOI=10.1016/S0022-2836(02)00242-5; PubMed=12054872 [NCBI, ExPASy, EBI, Israel, Japan] Smith P.C., Firestein S., Hunt J.F.; "The crystal structure of the olfactory marker protein at 2.3 A resolution."; J. Mol. Biol. 319:807-821(2002).

Comments

FUNCTION: May act as a modulator of the olfactory signal-transduction cascade.
SUBUNIT: Interacts with BEX1 and BEX2.
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Uniquely associated with mature olfactory receptor neurons.
SIMILARITY: Belongs to the olfactory marker protein family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U02557; AAA18415.1; -; Unassigned_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
U01213; AAA20486.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
BC046600; AAH46600.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

B54261; B54261.

NP_035140.1; -.

3D structure databases

PDB

1F35; X-ray; 2.30 A; A/B=1-163.	[ExPASy / RCSB / EBI]
1JOB; X-ray; 2.40 A; A=1-163.	[ExPASy / RCSB / EBI]
1JOD; X-ray; 3.20 A; A/B=1-163.	[ExPASy / RCSB / EBI]

Detailed list of linked structures.

PDBsum

1F35; -.
1JOB; -.
1JOD; -.

ModBase

Q64288.

Organism-specific databases

MGI

MGI:97436; Omp.

Gene expression databases

ArrayExpress

Q64288; -.

CleanEx

MM_OMP; -.

GermOnline

ENSMUSG00000074006; Mus musculus.

Ontologies

GO:0030424;	Cellular component: axon (inferred from direct assay from MGI).
GO:0043025;	Cellular component: cell soma (inferred from direct assay from MGI).
GO:0005829;	Cellular component: cytosol (inferred from direct assay from MGI).
GO:0005634;	Cellular component: nucleus (inferred from direct assay from MGI).
GO:0004871;	Molecular function: signal transducer activity (inferred from mutant phenotype from MGI).
GO:0007608;	Biological process: sensory perception of smell (inferred from mutant phenotype from MGI).
QuickGo view.

Family and domain databases

InterPro

IPR009103; Olfactory_marker.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.120.390; Olfactory_marker; 1.

PANTHER

PTHR15357; Olfactory_marker; 1.

Pfam

PF06554; Olfactory_mark; 1.
Pfam graphical view of domain structure.

ProDom

PD022055; Olfactory_marker; 1.
[Domain structure / List of seq. sharing at least 1 domain]

BLOCKS

Q64288.

Genome annotation databases

Ensembl

ENSMUSG00000074006; Mus musculus. [Contig view]

GeneID

18378; -.

KEGG

mmu:18378; -.

Phylogenomic databases

HOGENOM

Q64288; -.

HOVERGEN

Q64288; -.

Other

Q64288; -.

Omp; Mus musculus.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

3D-structure; Acetylation; Cytoplasm; Olfaction; Sensory transduction.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`INIT_MET`	`1 1`		`Removed (By similarity).`
`CHAIN`	`2 163`	`162`	`Olfactory marker protein.`	`PRO_0000058045`
`MOD_RES`	`2 2`		`N-acetylalanine (By similarity).`
`STRAND`	`10 14`	`5`
`HELIX`	`19 34`	`16`
`STRAND`	`50 56`	`7`
`STRAND`	`61 83`	`23`
`TURN`	`89 91`	`3`
`HELIX`	`96 98`	`3`
`STRAND`	`104 108`	`5`
`STRAND`	`115 117`	`3`
`HELIX`	`119 135`	`17`
`STRAND`	`137 145`	`9`
`HELIX`	`151 153`	`3`
`STRAND`	`154 162`	`9`

Sequence information

Length: 163 AA [This is the length of the unprocessed precursor]

Molecular weight: 18867 Da [This is the MW of the unprocessed precursor]

CRC64: D50EA5937D7EAE16 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAEDGPQKQQ LEMPLVLDQD LTQQMRLRVE SLKQRGEKKQ DGEKLIRPAE SVYRLDFIQQ 

        70         80         90        100        110        120 
QKLQFDHWNV VLDKPGKVTI TGTSQNWTPD LTNLMTRQLL DPAAIFWRKE DSDAMDWNEA 

       130        140        150        160 
DALEFGERLS DLAKIRKVMY FLITFGEGVE PANLKASVVF NQL

Q64288 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools