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UniProtKB/Swiss-Prot entry Q61XD3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AIR2_CAEBR
Primary accession number Q61XD3
Secondary accession number A8WW15
Integrated into Swiss-Prot on December 12, 2006
Sequence was last modified on November 23, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 28)
Name and origin of the protein
Protein name Aurora/Ipl1-related protein kinase 2
Synonyms EC 2.7.11.1
Aurora-B
Gene name
Name: air-2
ORFNames: CBG04030
From
Caenorhabditis briggsae [TaxID: 6238] 
Taxonomy Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AF16;
DOI=10.1371/journal.pbio.0000045; PubMed=14624247 [NCBI, ExPASy, EBI, Israel, Japan]
Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P., Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W., Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A., Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E., Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K., Durbin R.M., Waterston R.H.;
"The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics.";
PLoS Biol. 1:166-192(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CAAC02000457; CAP24824.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase Q61XD3.
Organism-specific databases
WormBase WBGene00026778; CBG04030.
Family and domain databases
InterPro IPR000719; Prot_kinase_core.
IPR017441; Protein_kinase_ATP_bd_CS.
IPR017442; Se/Thr_pkinase-rel.
IPR008271; Ser_thr_pkin_AS.
IPR002290; Ser_thr_pkinase.
Graphical view of domain structure.
Pfam PF00069; Pkinase; 1.
Pfam graphical view of domain structure.
ProDom PD000001; Prot_kinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00220; S_TKc; 1.
SMART graphical view of domain structure.
PROSITE PS00107; PROTEIN_KINASE_ATP; 1.
PS50011; PROTEIN_KINASE_DOM; 1.
PS00108; PROTEIN_KINASE_ST; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q61XD3.
Other
ProtoNet Q61XD3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Chromatin regulator; Chromosome partition; Complete proteome; Developmental protein; Kinase; Meiosis; Mitosis; Nucleotide-binding; Serine/threonine-protein kinase; Transferase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   302  302     Aurora/Ipl1-related protein kinase 2. PRO_0000268639
DOMAIN   27   277  251     Protein kinase. 
NP_BIND   33    41  9     ATP (By similarity). 
ACT_SITE   150   150        Proton acceptor (By similarity). 
BINDING   56    56        ATP (By similarity). 
Sequence information
Length: 302 AA [This is the length of the unprocessed precursor] Molecular weight: 34465 Da [This is the MW of the unprocessed precursor] CRC64: 46AFF54C88C21685 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MENKPQILQT KSKNTPNKGG KLSINDFEIG RPLGKGKFGS VYLARTKTGH FHCAIKVLFK 

        70         80         90        100        110        120 
SQLISGGVEH QLEREIEIQS HLQHPNIIRL YNYFWDAKKI YLILEYAPGG EMYKQLTTQK 

       130        140        150        160        170        180 
RFTEAMAGKY MYEIADALSY CHRKNVIHRD IKPENLLIGA QGELKIGDFG WSVHAPSNKR 

       190        200        210        220        230        240 
QTMCGTMDYL PPEMVNGNSH SDAVDLWAIG VLCYEFLVGK PPFEHENQAD TYSAIKAGRF 

       250        260        270        280        290        300 
TYPDFVKKGA RDLIGKLLVV DPRRRCSLQE VKDHYWVTSM LDSCRRAAEK QKAERAASLR 


DH 

Q61XD3 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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