[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.; "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6 .
SIMILARITY: Belongs to the ATCase/OTCase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP006627; BAD64871.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_175832.1; -.

3D structure databases

ModBase

Q5WFI9.

Enzyme and pathway databases

BioCyc

BCLA66692:ABC2336-MON; -.

Ontologies

GO:0004070;	Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221;	Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00001; -; 1.
PBIL [Tree]

InterPro

IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.

Pfam

PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.

PRINTS

PR00100; AOTCASE.
PR00101; ATCASE.

ProDom

PD000902; Enolase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGRFAMs

TIGR00670; asp_carb_tr; 1.

PROSITE

PS00097; CARBAMOYLTRANSFERASE; 1.

BLOCKS

Q5WFI9.

Genome annotation databases

GeneID

3202824; -.

GenomeReviews

AP006627_GR; ABC2336.

KEGG

bcl:ABC2336; -.

NMPDR

fig|66692.3.peg.2024; -.

Phylogenomic databases

HOGENOM

Q5WFI9; -.

Genome annotation databases

CMR

Q5WFI9; ABC2336.

Other

ProtoNet

Q5WFI9.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Pyrimidine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 301`	`301`		`Aspartate carbamoyltransferase.`	`PRO_0000113098`

Sequence information

Length: 301 AA [This is the length of the unprocessed precursor]

Molecular weight: 33345 Da [This is the MW of the unprocessed precursor]

CRC64: C5FFB57004E44C55 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MLSAQIEKAT QKGLCTMNEM GVSEVLDLLK TAESFAAGAV WKPRMQLFVA NLFFEPSTRT 

        70         80         90        100        110        120 
RFSFEVAERR LGLEVLQFDG QHASTQKGES LYDTARTLES IGASALVIRH RQDAYFHELK 

       130        140        150        160        170        180 
GLSVPIINAG DGCGNHPTQS LLDLLTIKQE FSSFSGLHVV IAGDLAHSRV ARSNADILTR 

       190        200        210        220        230        240 
LGARVSVAGP IEWMGEFTDT YTHVSMDEAA RQADVLMMLR VQHERHDDNA LFSKEAYHQA 

       250        260        270        280        290        300 
YGLTEQREAL MAKQSIIMHP APVNRDVEIA SVLVECKRSR IYKQSANGVA VRMAVLKRAL 


A

Q5WFI9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools