[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.; "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: D-mannitol 1-phosphate + NAD⁺ = D-fructose 6-phosphate + NADH.
SIMILARITY: Belongs to the mannitol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP006627; BAD65460.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_176421.1; -.

3D structure databases

ModBase

Q5WDV0.

Enzyme and pathway databases

BioCyc

BCLA66692:ABC2926-MON; -.

Ontologies

GO:0008926;	Molecular function: mannitol-1-phosphate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00196; -; 1.
PBIL [Tree]

InterPro

IPR013328; DHase_multihelical.
IPR013118; Mannitol_DHase_C.
IPR000669; Mannitol_DHase_core.
IPR013131; Mannitol_DHase_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.

Pfam

PF01232; Mannitol_dh; 1.
PF08125; Mannitol_dh_C; 1.
Pfam graphical view of domain structure.

PRINTS

PR00084; MTLDHDRGNASE.

PROSITE

PS00974; MANNITOL_DHGENASE; FALSE_NEG.

BLOCKS

Q5WDV0.

Genome annotation databases

GeneID

3204485; -.

GenomeReviews

AP006627_GR; ABC2926.

KEGG

bcl:ABC2926; -.

NMPDR

fig|66692.3.peg.2814; -.

Phylogenomic databases

HOGENOM

Q5WDV0; -.

Genome annotation databases

CMR

Q5WDV0; ABC2926.

Other

ProtoNet

Q5WDV0.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 374`	`374`	`Mannitol-1-phosphate 5-dehydrogenase.`	`PRO_1000011796`
`NP_BIND`	`3 14`	`12`	`NAD (By similarity).`

Sequence information

Length: 374 AA [This is the length of the unprocessed precursor]

Molecular weight: 41332 Da [This is the MW of the unprocessed precursor]

CRC64: 27BC7CAFEA595416 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKAVHFGAGN IGRGFIGALL VDAGYEVTFV DVNEKIIDAL NERNEYKVTV AGERKETETV 

        70         80         90        100        110        120 
TNVRGINSKT NEKEAIDAIA EADIVTTAVG PTVLPYIAKT IAQGLKQRTA SKPVNMIACE 

       130        140        150        160        170        180 
NAIRATSQLK KDVLSHLSEE ETTALLKDAG FADAAVDRIV PNVQSDDILH VTVEPFFEWV 

       190        200        210        220        230        240 
VEKPALKGDA VQLGKAVLVE DLAPYIERKL FTVNTGHAVA AYVGYRKGKK TIKEALADDY 

       250        260        270        280        290        300 
IKHRVRGALN ETKAMLVEEY QFDAEAHEDY IDKILLRFQN PHLEDLVERV GRGPIRKLGP 

       310        320        330        340        350        360 
ADRLVKPAKY LAEKGLHPES LAETIFDALH FYAEGDPESE ELRALVDEKG YVDAFCEISK 

       370 
LEKDHPLVEI VAKE

Q5WDV0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools