ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q5UQX1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MCE_MIMIV
Primary accession number Q5UQX1
Secondary accession numbers None
Integrated into Swiss-Prot on September 13, 2005
Sequence was last modified on December 7, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 27)
Name and origin of the protein
Protein name Probable mRNA-capping enzyme
Synonyms None
Includes Polynucleotide 5'-triphosphatase
     (EC 3.1.3.33)
     (mRNA 5'-triphosphatase)
     (TPase)
mRNA guanylyltransferase
     (EC 2.7.7.50)
     (GTP--RNA guanylyltransferase)
     (GTase)
mRNA (guanine-N(7)-)-methyltransferase
     (EC 2.1.1.56)
Gene name
OrderedLocusNames: MIMI_R382
From
Acanthamoeba polyphaga mimivirus (APMV) [TaxID: 212035] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Mimiviridae; Mimivirus.
Virus host Acanthamoeba polyphaga (Amoeba) [TaxID: 5757]
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Rowbotham-Bradford;
DOI=10.1126/science.1101485; PubMed=15486256 [NCBI, ExPASy, EBI, Israel, Japan]
Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H., La Scola B., Susan M., Claverie J.-M.;
"The 1.2-megabase genome sequence of Mimivirus.";
Science 306:1344-1350(2004).
[2]
 IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND SUBCELLULAR LOCATION.
DOI=10.1128/JVI.00940-06; PubMed=16971431 [NCBI, ExPASy, EBI, Israel, Japan]
Renesto P., Abergel C., Decloquement P., Moinier D., Azza S., Ogata H., Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D.;
"Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products.";
J. Virol. 80:11678-11685(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY653733; AAV50651.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_142736.1; -.
3D structure databases
PDB
3BGY; X-ray; 1.65 A; A/B=1-237.[ExPASy / RCSB / EBI]
PDBsum 3BGY; -.
ModBase Q5UQX1.
Family and domain databases
InterPro IPR001339; mRNA_cap_enzyme.
IPR004971; Pox_MCEL.
Graphical view of domain structure.
Pfam PF01331; mRNA_cap_enzyme; 1.
PF03291; Pox_MCEL; 1.
Pfam graphical view of domain structure.
BLOCKS Q5UQX1.
Genome annotation databases
GeneID 3162607; -.
Other
ProtoNet Q5UQX1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Complete proteome; Hydrolase; mRNA capping; mRNA processing; Multifunctional enzyme; Nucleotidyltransferase; S-adenosyl-L-methionine; Transferase; Virion.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   1170  1170     Probable mRNA-capping enzyme. PRO_0000210133
ACT_SITE   292    292        N6-GMP-lysine intermediate (Potential). 
Sequence information
Length: 1170 AA [This is the length of the unprocessed precursor] Molecular weight: 136508 Da [This is the MW of the unprocessed precursor] CRC64: 320D8F4137C55AD6 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MGTKLKKSNN DITIFSENEY NEIVEMLRDY SNGDNLEFEV SFKNINYPNF MRITEHYINI 

        70         80         90        100        110        120 
TPENKIESNN YLDISLIFPD KNVYRVSLFN QEQIGEFITK FSKASSNDIS RYIVSLDPSD 

       130        140        150        160        170        180 
DIEIVYKNRG SGKLIGIDNW AITIKSTEEI PLVAGKSKIS KPKITGSERI MYRYKTRYSF 

       190        200        210        220        230        240 
TINKNSRIDI TDVKSSPIIW KLMTVPSNYE LELELINKID INTLESELLN VFMIIQDTKI 

       250        260        270        280        290        300 
PISKAESDTV VEEYRNLLNV RQTNNLDSRN VISVNSNHII NFIPNRYAVT DKADGERYFL 

       310        320        330        340        350        360 
FSLNSGIYLL SINLTVKKLN IPVLEKRYQN MLIDGEYIKT TGHDLFMVFD VIFAEGTDYR 

       370        380        390        400        410        420 
YDNTYSLPKR IIIINNIIDK CFGNLIPFND YTDKHNNLEL DSIKTYYKSE LSNYWKNFKN 

       430        440        450        460        470        480 
RLNKSTDLFI TRKLYLVPYG IDSSEIFMYA DMIWKLYVYN ELTPYQLDGI IYTPINSPYL 

       490        500        510        520        530        540 
IRGGIDAYDT IPMEYKWKPP SQNSIDFYIR FKKDVSGADA VYYDNSVERA EGKPYKICLL 

       550        560        570        580        590        600 
YVGLNKQGQE IPIQFKVNGV EQTANIYTKD GEATDINGNA INDNTVVEFV FDTLKIDMDD 

       610        620        630        640        650        660 
SYKWIPIRTR YDKTESVQKY HKRYGNNLQI ANRIWKTITN PITEDIISSL GDPTTFNKEI 

       670        680        690        700        710        720 
TLLSDFRDTK YNKQALTYYQ KNTSNAAGMR AFNNWIKSNM ITTYCRDGSK VLDIGCGRGG 

       730        740        750        760        770        780 
DLIKFINAGV EFYVGIDIDN NGLYVINDSA NNRYKNLKKT IQNIPPMYFI NADARGLFTL 

       790        800        810        820        830        840 
EAQEKILPGM PDFNKSLINK YLVGNKYDTI NCQFTIHYYL SDELSWNNFC KNINNQLKDN 

       850        860        870        880        890        900 
GYLLITSFDG NLIHNKLKGK QKLSSSYTDN RGNKNIFFEI NKIYSDTDKV GLGMAIDLYN 

       910        920        930        940        950        960 
SLISNPGTYI REYLVFPEFL EKSLKEKCGL ELVESDLFYN IFNTYKNYFK KTYNEYGMTD 

       970        980        990       1000       1010       1020 
VSSKKHSEIR EFYLSLEGNA NNDIEIDIAR ASFKLAMLNR YYVFRKTSTI NITEPSRIVN 

      1030       1040       1050       1060       1070       1080 
ELNNRIDLGK FIMPYFRTNN MFIDLDNVDT DINRVYRNIR NKYRTTRPHV YLIKHNINEN 

      1090       1100       1110       1120       1130       1140 
RLEDIYLSNN KLDFSKIKNG SDPKVLLIYK SPDKQFYPLY YQNYQSMPFD LDQIYLPDKK 

      1150       1160       1170 
KYLLDSDRII NDLNILINLT EKIKNIPQLS
Q5UQX1 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!