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UniProtKB/Swiss-Prot entry Q5PRF9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SAM4B_HUMAN
Primary accession number Q5PRF9
Secondary accession number Q6P194
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on January 4, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 35)
Name and origin of the protein
Protein name Sterile alpha motif domain-containing protein 4B
Synonyms None
Gene name
Name: SAMD4B
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Ovary, and Uterus;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[2]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-407, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1038/nbt1240; PubMed=16964243 [NCBI, ExPASy, EBI, Israel, Japan]
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization.";
Nat. Biotechnol. 24:1285-1292(2006).
[3]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-606, AND MASS SPECTROMETRY.
DOI=10.1021/pr0705441; PubMed=18220336 [NCBI, ExPASy, EBI, Israel, Japan]
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III;
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.";
J. Proteome Res. 7:1346-1351(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC054518; AAH54518.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC065211; AAH65211.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_060498.2; -.
UniGene Hs.612332
3D structure databases
ModBase Q5PRF9.
Protein-protein interaction databases
IntAct Q5PRF9; -.
PTM databases
PhosphoSite Q5PRF9; -.
Organism-specific databases
HGNC HGNC:25492; SAMD4B.
GenAtlas SAMD4B.
HPA HPA016800; -.
GeneCards Q5PRF9.
Gene expression databases
ArrayExpress Q5PRF9; -.
CleanEx HS_SAMD4B; -.
GermOnline ENSG00000179134; Homo sapiens.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR001660; SAM.
IPR013761; SAM_type.
Graphical view of domain structure.
Gene3D G3DSA:1.10.150.50; SAM_type; 1.
Pfam PF00536; SAM_1; 1.
Pfam graphical view of domain structure.
SMART SM00454; SAM; 1.
SMART graphical view of domain structure.
PROSITE PS50105; SAM_DOMAIN; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q5PRF9.
Genome annotation databases
Ensembl ENSG00000179134; Homo sapiens. [Contig view]
GeneID 55095; -.
KEGG hsa:55095; -.
Phylogenomic databases
HOVERGEN Q5PRF9; -.
Other
ProtoNet Q5PRF9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Phosphoprotein.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   694  694     Sterile alpha motif domain-containing protein 4B. PRO_0000260080
DOMAIN   299   372  74     SAM. 
MOD_RES   407   407        Phosphothreonine. 
MOD_RES   606   606        Phosphothreonine. 
Sequence information
Length: 694 AA [This is the length of the unprocessed precursor] Molecular weight: 75483 Da [This is the MW of the unprocessed precursor] CRC64: 4AA4769F38494E56 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MMFRDQVGIL AGWFKGWNEC EQTVALLSLL KRVTRTQARF LQLCLEHSLA DCNDIHLLES 

        70         80         90        100        110        120 
EANSAAIVSQ WQQESKEKVV SLLLSHLPLL QPGNTEAKSE YMRLLQKVLA YSIESNAFIE 

       130        140        150        160        170        180 
ESRQLLSYAL IHPATTLEDR NALALWLSHL EERLASGFRS RPEPSYHSRQ GSDEWGGPAE 

       190        200        210        220        230        240 
LGPGEAGPGW QDKPPRENGH VPFHPSSSVP PAINSIGSNA NTGLPCQIHP SPLKRSMSLI 

       250        260        270        280        290        300 
PTSPQVPGEW PSPEELGARA AFTTPDHAPL SPQSSVASSG SEQTEEQGSS RNTFQEDGSG 

       310        320        330        340        350        360 
MKDVPSWLKS LRLHKYAALF SQMSYEEMMT LTEQHLESQN VTKGARHKIA LSIQKLRERQ 

       370        380        390        400        410        420 
SVLKSLEKDV LEGGNLRNAL QELQQIIITP IKAYSVLQAT VAAATTTPTA KDGAPGEPPL 

       430        440        450        460        470        480 
PGAEPPLAHP GTDKGTEAKD PPAVENYPPP PAPAPTDGSE PAPAPVADGD IPSQFTRVMG 

       490        500        510        520        530        540 
KVCTQLLVSR PDEENITSYL QLIEKCLTHE AFTETQKKRL LSWKQQVLKL LRTFPRKAAL 

       550        560        570        580        590        600 
EMQNYRQQKG WAFGSNSLPI AGSVGMGVAR RTQRQFPMPP RALPPGRMGL LSPSGIGGVS 

       610        620        630        640        650        660 
PRHALTSPSL GGQGRQNLWF ANPGGSNSMP SQSRSSVQRT HSLPVHSSPQ AILMFPPDCP 

       670        680        690 
VPGPDLEINP TLESLCLSMT EHALGDGTDK TSTI 

Q5PRF9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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