NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1007/s00203-004-0742-9; PubMed=15551059 [NCBI, ExPASy, EBI, Israel, Japan]
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.;
"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1.";
Arch. Microbiol. 183:27-36(2005).

Comments

FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions (By similarity).
CATALYTIC ACTIVITY: NTP + H₂O = NDP + phosphate.
COFACTOR: Divalent cations (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the HAM1 NTPase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CR555306; CAI07417.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_158318.1; -.

3D structure databases

ModBase

Q5P5J5.

Enzyme and pathway databases

BioCyc

ASP76114:C1A234-MON; -.

Ontologies

GO:0017111;	Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01405; -; 1.
PBIL [Tree]

InterPro

IPR002637; Ham1p_like.
Graphical view of domain structure.

PANTHER

PTHR11067; Ham1p_like; 1.

Pfam

PF01725; Ham1p_like; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00042; Ham1p_like; 1.

BLOCKS

Q5P5J5.

Genome annotation databases

GeneID

3183143; -.

GenomeReviews

CR555306_GR; AZOSEA12920.

KEGG

eba:c1A234; -.

NMPDR

fig|76114.4.peg.1778; -.

Phylogenomic databases

HOGENOM

Q5P5J5; -.

Genome annotation databases

CMR

Q5P5J5; AZOSEA12920.

Other

ProtoNet

Q5P5J5.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 198`	`198`		`Nucleoside-triphosphatase.`	`PRO_0000178118`

Sequence information

Length: 198 AA [This is the length of the unprocessed precursor]

Molecular weight: 20854 Da [This is the MW of the unprocessed precursor]

CRC64: 0E3D64D88CEA67ED [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTARLVLASN NAKKAVEMTT LLAPLGIEVL PQSAFDIPEA DEPHPTFVEN ALAKARHAAA 

        70         80         90        100        110        120 
LSGLPAVADD SGLCVAALGG APGVQSARFA GEPKSDARNN ALLVERLAGS ADRRAFFYSV 

       130        140        150        160        170        180 
VALVRHADDP RPLIADGEWH GTILYAPRGA NGFGYDPLFF LPELGQTAAE LDAQLKNTLS 

       190 
HRGAAMRHLL ARLSTAPL

Q5P5J5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools