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UniProtKB/Swiss-Prot entry Q5NHX4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DUT_FRATT
Primary accession number Q5NHX4
Secondary accession numbers None
Integrated into Swiss-Prot on March 15, 2005
Sequence was last modified on February 1, 2005 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 24)
Name and origin of the protein
Protein name Deoxyuridine 5'-triphosphate nucleotidohydrolase
Synonyms dUTPase
EC 3.6.1.23
dUTP pyrophosphatase
Gene name
Name: dut
OrderedLocusNames: FTT0319
From
Francisella tularensis subsp. tularensis [TaxID: 119856] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales; Francisellaceae; Francisella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SCHU S4 / Schu 4;
DOI=10.1038/ng1499; PubMed=15640799 [NCBI, ExPASy, EBI, Israel, Japan]
Larsson P., Oyston P.C.F., Chain P., Chu M.C., Duffield M., Fuxelius H.-H., Garcia E., Haelltorp G., Johansson D., Isherwood K.E., Karp P.D., Larsson E., Liu Y., Michell S., Prior J., Prior R., Malfatti S., Sjoestedt A., Svensson K., Thompson N., Vergez L., Wagg J.K., Wren B.W., Lindler L.E., Andersson S.G.E., Forsman M., Titball R.W.;
"The complete genome sequence of Francisella tularensis, the causative agent of tularemia.";
Nat. Genet. 37:153-159(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ749949; CAG44952.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_169368.1; -.
3D structure databases
ModBase Q5NHX4.
Enzyme and pathway databases
BRENDA 3.6.1.23; 297365.
Ontologies
GO
GO:0004170; Molecular function: dUTP diphosphatase activity (inferred from electronic annotation from HAMAP).
GO:0046080; Biological process: dUTP metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00116; -; 1.
PBIL [Tree]
InterPro IPR008180; DeoxyUTPase.
IPR008181; dUTP_pyrophosphatase_subfam_1.
Graphical view of domain structure.
Pfam PF00692; dUTPase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00576; dut; 1.
Genome annotation databases
GeneID 3191551; -.
GenomeReviews AJ749949_GR; FTT0319.
KEGG ftu:FTT0319; -.
Phylogenomic databases
HOGENOM Q5NHX4; -.
OMA Q5NHX4; LDLRACI.
Genome annotation databases
CMR Q5NHX4; FTT0319.
Other
ProtoNet Q5NHX4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Nucleotide metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   148  148     Deoxyuridine 5'-triphosphate nucleotidohydrolase. PRO_0000182862
Sequence information
Length: 148 AA [This is the length of the unprocessed precursor] Molecular weight: 15942 Da [This is the MW of the unprocessed precursor] CRC64: A8BB5F2950FBB081 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKVELKILNK ELIKELPGYA TEGSAAIDLR ACISESIYLK SGECKLVATG IAINIANPNY 

        70         80         90        100        110        120 
AAMILPRSGL GHKKGLVLGN GTGLIDSDYQ GELMVSCFNR SQETIEIEPL MRFAQLVIVP 

       130        140 
VVQANFEIVE DFSQQSVRAT GGFGHTGV 

Q5NHX4 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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