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UniProtKB/Swiss-Prot entry Q5KN22


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UBC2_CRYNE
Primary accession number Q5KN22
Secondary accession number Q55YQ1
Integrated into Swiss-Prot on January 10, 2006
Sequence was last modified on February 15, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 33)
Name and origin of the protein
Protein name Ubiquitin-conjugating enzyme E2 2
Synonyms EC 6.3.2.19
Ubiquitin-protein ligase UBC2
Ubiquitin carrier protein UBC2
Gene name
Name: UBC2
OrderedLocusNames: CNA08010, CNBA7840
From
Cryptococcus neoformans (Filobasidiella neoformans) [TaxID: 5207] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Tremellaceae; Filobasidiella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=B-3501A, and JEC21;
DOI=10.1126/science.1103773; PubMed=15653466 [NCBI, ExPASy, EBI, Israel, Japan]
Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
"The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans.";
Science 307:1321-1324(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017341; AAW41362.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAEY01000005; EAL23017.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_567181.1; -.
XP_777664.1; -.
3D structure databases
ModBase Q5KN22.
Family and domain databases
InterPro IPR016135; UBQ-conjugat/RWD-like.
IPR000608; UBQ-conjugat_E2.
Graphical view of domain structure.
Gene3D G3DSA:3.10.110.10; UBQ-conjugat_E2; 1.
PANTHER PTHR11621; UBQ-conjugat_E2; 1.
Pfam PF00179; UQ_con; 1.
Pfam graphical view of domain structure.
ProDom PD000461; UBQ_conjugat; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00212; UBCc; 1.
SMART graphical view of domain structure.
PROSITE PS00183; UBIQUITIN_CONJUGAT_1; 1.
PS50127; UBIQUITIN_CONJUGAT_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q5KN22.
Genome annotation databases
GeneID 3253708; -.
4934050; -.
GenomeReviews AE017341_GR; CNA08010.
KEGG cnb:CNBA7840; -.
cne:CNA08010; -.
Phylogenomic databases
HOGENOM Q5KN22; -.
Other
ProtoNet Q5KN22.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chromatin regulator; Complete proteome; Cytoplasm; DNA damage; DNA repair; Ligase; Nucleus; Sporulation; Transcription; Transcription regulation; Ubl conjugation pathway.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   169  169     Ubiquitin-conjugating enzyme E2 2. PRO_0000082530
ACT_SITE   88    88        Glycyl thioester intermediate (By similarity). 
Sequence information
Length: 169 AA [This is the length of the unprocessed precursor] Molecular weight: 18847 Da [This is the MW of the unprocessed precursor] CRC64: DD23A363FAF849AE [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSTAAKRRLI RDFKRLTSDA PIGISGSPNP DNIMVWNAVI FGPPETPFED GSFRLTLTFT 

        70         80         90        100        110        120 
DAYPNKPPTV RFISKMFHPN IYANGELCLD ILQNRWSPTY DVAAILTSVQ SLLNDPNPAS 

       130        140        150        160 
PANVDAAQLF KENLKEYERR VKKTVELSWV DNADEIEAEV VEADEGSSS 

Q5KN22 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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