[1]	NUCLEOTIDE SEQUENCE. TISSUE=Embryo; Filippi A., Tiso N., Deflorian G., Zecchin E., Bortolussi M., Argenton F.; "The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord."; Proc. Natl. Acad. Sci. U.S.A. 102:4377-4382(2005).
[2]	NUCLEOTIDE SEQUENCE. Collins J.; Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
[3]	NUCLEOTIDE SEQUENCE. DOI=10.1007/s00427-007-0158-z; PubMed=17554554 [NCBI, ExPASy, EBI, Israel, Japan] Bronchain O.J., Pollet N., Ymlahi-Ouazzani Q., Dhorne-Pollet S., Helbling J.C., Lecarpentier J.E., Percheron K., Wegnez M.; "The olig family: phylogenetic analysis and early gene expression in Xenopus tropicalis."; Dev. Genes Evol. 217:485-497(2007).
[4]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. STRAIN=Singapore local strain; TISSUE=Embryo; NIH - Zebrafish Gene Collection (ZGC) project; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

Comments

SIMILARITY: Contains 1 basic helix-loop-helix (bHLH) domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BC092917; AAH92917.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ488293; CAD32563.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
BX936305; CAM12912.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
BN001115; CAM91227.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

IPI00497718; -.

NP_955808.1; -.

3D structure databases

ModBase

Q5K548.

Organism-specific databases

ZFIN

ZDB-GENE-030131-3580; olig4.

Gene expression databases

Bgee

Q5K548; -.

Ontologies

GO:0005634;	Cellular component: nucleus (inferred from electronic annotation from InterPro).
GO:0030528;	Molecular function: transcription regulator activity (inferred from electronic annotation from InterPro).
GO:0045664;	Biological process: regulation of neuron differentiation (inferred from mutant phenotype from ZFIN).
GO:0045449;	Biological process: regulation of transcription (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR001092; HLH_basic.
IPR011598; HLH_DNA_bd.
Graphical view of domain structure.

Gene3D

G3DSA:4.10.280.10; HLH_DNA_bd; 1.

Pfam

PF00010; HLH; 1.
Pfam graphical view of domain structure.

SMART

SM00353; HLH; 1.
SMART graphical view of domain structure.

PROSITE

PS50888; HLH; 1.
PROSITE graphical view of domain structure (profiles).

Genome annotation databases

Ensembl

ENSDARG00000052610; Danio rerio. [Contig view]

GeneID

324857; -.

KEGG

dre:324857; -.

Phylogenomic databases

HOGENOM

Q5K548; -.

HOVERGEN

Q5K548; -.

OMA

Q5K548; KLVGDVY.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

None

Features

None

Sequence information

Length: 244 AA

Molecular weight: 26220 Da

CRC64: 9069A58B4EF575A2 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDSDASSTCS RSSSPDLTVD SGFFSNKMFQ AYGETVQQKS EKGLQNAGKT RTRADLSKDD 

        70         80         90        100        110        120 
LQDLRLKVNS RERKRMHDLN QAMDGLREVM PYAQGPSVRK LSKISTLLLA RNYILMLSSS 

       130        140        150        160        170        180 
LEEMKKLVGD VYGANAQSHS ARRVLPPTSA APATQLPLLS LAPSLHPLVG STSAVSHTTT 

       190        200        210        220        230        240 
NGAQTPHSPP STGYLGFPAL PTLLKDPLHL SGGYRHFPGM PCPCSLCQPL PASTASLHSL 


SMGK

Q5K548 in FASTA format

View entry in raw text format (no links)
Request for annotation of this UniProtKB/TrEMBL entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools