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UniProtKB/Swiss-Prot entry Q5E4J3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAO1_VIBF1
Primary accession number Q5E4J3
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on March 15, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 24)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: VF_1558
From
Vibrio fischeri (strain ATCC 700601 / ES114) [TaxID: 312309] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Aliivibrio.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0409900102; PubMed=15703294 [NCBI, ExPASy, EBI, Israel, Japan]
Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P.;
"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners.";
Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000020; AAW86053.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_204941.1; -.
3D structure databases
ModBase Q5E4J3.
Enzyme and pathway databases
BioCyc VFIS312309:VF1558-MON; -.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q5E4J3.
Genome annotation databases
GeneID 3278798; -.
GenomeReviews CP000020_GR; VF_1558.
KEGG vfi:VF1558; -.
NMPDR fig|312309.3.peg.1558; -.
Phylogenomic databases
HOGENOM Q5E4J3; -.
Genome annotation databases
CMR Q5E4J3; VF_1558.
Other
ProtoNet Q5E4J3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   562  562     NAD-dependent malic enzyme. PRO_0000160235
ACT_SITE   101   101        Proton donor (By similarity). 
ACT_SITE   172   172        Proton acceptor (By similarity). 
METAL   243   243        Divalent metal cation (By similarity). 
METAL   244   244        Divalent metal cation (By similarity). 
METAL   267   267        Divalent metal cation (By similarity). 
BINDING   154   154        NAD (By similarity). 
BINDING   267   267        NAD (By similarity). 
BINDING   415   415        NAD (By similarity). 
SITE   267   267  1     Important for activity (By similarity). 
Sequence information
Length: 562 AA [This is the length of the unprocessed precursor] Molecular weight: 62299 Da [This is the MW of the unprocessed precursor] CRC64: DD7737D7F1B11DFE [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNNNKRPLYI PYAGPALLST PLLNKGSAFS TTERKYFNLE GLLPEAIESI EEQTGRAYKQ 

        70         80         90        100        110        120 
YQNFENDMDK HIYLRNIQDT NETLFYRLVQ NHISEMMPII YTPTVGAACE NFSNIYRRGR 

       130        140        150        160        170        180 
GLFISYENKN RIDDLLNNAA NQNVKVIVVT DGERILGLGD QGIGGMGIPI GKLALYTACG 

       190        200        210        220        230        240 
GISPAHTLPI VLDVGTNNPQ RLADPMYMGW RHPRVTGDEY ADFVEDFIQA VQRRWPEALV 

       250        260        270        280        290        300 
QFEDFAQKNA MPLLERYKNR ICCFNDDIQG TAAVTVGSLL AACKAAGSSL SEQRVTFLGA 

       310        320        330        340        350        360 
GSAGCGIAEA IIAQMVSEGI SDAQARSQVY MVDRWGLLQE GMPNLLDFQQ RLVQKAENTK 

       370        380        390        400        410        420 
DWVSEEPNFS LVDVMRNAKP TVLIGVSGAP GLFSKEVIQE MHKHCERPIV FPLSNPTSRV 

       430        440        450        460        470        480 
EATPNDIIRW TDGQALVATG SPFDPVAHNG QTYPIAQCNN SFIFPGIGLG VLAIKATRVT 

       490        500        510        520        530        540 
DEMLMESSRA LAECSPLAIH GTGALLPPLE EIHSVSKRIA FAVAKKAIEQ GHALEITDEA 

       550        560 
LQQKIESYFW KPVYRRYKRT AF
Q5E4J3 in FASTA format

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