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UniProtKB/Swiss-Prot entry Q55FL3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ALRC_DICDI
Primary accession number Q55FL3
Secondary accession numbers None
Integrated into Swiss-Prot on April 8, 2008
Sequence was last modified on May 24, 2005 (Sequence version 1)
Annotations were last modified on    September 23, 2008 (Entry version 20)
Name and origin of the protein
Protein name Aldose reductase C
Synonyms ARC
EC 1.1.1.21
Aldehyde reductase C
Gene name
Name: alrC
ORFNames: DDB_0231284
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAFI02000003; EAL73482.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_647520.1; -.
3D structure databases
ModBase Q55FL3.
Organism-specific databases
dictyBase DDB0231284; alrC.
Family and domain databases
InterPro IPR001395; Aldo/ket_red.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.100; Aldo/ket_red; 1.
PANTHER PTHR11732; Aldo/ket_red; 1.
Pfam PF00248; Aldo_ket_red; 1.
Pfam graphical view of domain structure.
PRINTS PR00069; ALDKETRDTASE.
ProDom PD000288; Aldo/ket_red; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00798; ALDOKETO_REDUCTASE_1; 1.
PS00062; ALDOKETO_REDUCTASE_2; 1.
PS00063; ALDOKETO_REDUCTASE_3; FALSE_NEG.
BLOCKS Q55FL3.
Genome annotation databases
GeneID 3398524; -.
KEGG ddi:DDB_0231284; -.
Other
ProtoNet Q55FL3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   321  321     Aldose reductase C. PRO_0000327647
NP_BIND   22    31  10     NADP (Potential). 
NP_BIND   227   281  55     NADP (By similarity). 
COMPBIAS   4    16  13     Poly-Asn. 
ACT_SITE   62    62        Proton donor (By similarity). 
BINDING   124   124        Substrate (By similarity). 
Sequence information
Length: 321 AA [This is the length of the unprocessed precursor] Molecular weight: 36529 Da [This is the MW of the unprocessed precursor] CRC64: 2C05C8761CB9377D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFQNNYNNNT NYNNNNFKLN DGNQIPSIGL GTYYSENPGE VGDAINNALK NGYRHIDGAA 

        70         80         90        100        110        120 
FYGNEKVIGN SLKEIFKEGE IKREDIFYTS KLWNSCHNSN LVVKHCVKTI EDLGIGYLDL 

       130        140        150        160        170        180 
YLIHWPIAFE NSNPLGLTIE PLRDQNGNPI IAPVSIRETW QEMEKLVELG LVKSIGVSNF 

       190        200        210        220        230        240 
NVQNLVDLLT YAKIKPVVNQ VEIHPYLTQF KLQEYCDKYE IKLVAYSPLG QGKCDFFSNK 

       250        260        270        280        290        300 
ILKSIAGKYK KSVANVIFKW LNQRGIAAIP KSGNHSRIIE NFNIFDFQLS NDDIEKINSL 

       310        320 
NANIRTCSPI TFFGTPFYLF D 

Q55FL3 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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