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UniProtKB/Swiss-Prot entry Q4WPF2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ATG1_ASPFU
Primary accession number Q4WPF2
Secondary accession numbers None
Integrated into Swiss-Prot on August 16, 2005
Sequence was last modified on July 5, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 25)
Name and origin of the protein
Protein name Serine/threonine-protein kinase atg1
Synonyms EC 2.7.11.1
Autophagy-related protein 1
Gene name
Name: atg1
ORFNames: AFUA_4G09050
From
Aspergillus fumigatus (Sartorya fumigata) [TaxID: 5085] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Af293 / CBS 101355 / FGSC A1100;
DOI=10.1038/nature04332; PubMed=16372009 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.;
"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.";
Nature 438:1151-1156(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAHF01000005; EAL89882.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_751920.1; -.
3D structure databases
ModBase Q4WPF2.
Family and domain databases
InterPro IPR000719; Prot_kinase_core.
IPR017441; Protein_kinase_ATP_bd_CS.
IPR017442; Se/Thr_pkinase-rel.
IPR008271; Ser_thr_pkin_AS.
IPR002290; Ser_thr_pkinase.
Graphical view of domain structure.
Pfam PF00069; Pkinase; 1.
Pfam graphical view of domain structure.
ProDom PD000001; Prot_kinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00220; S_TKc; 1.
SMART graphical view of domain structure.
PROSITE PS00107; PROTEIN_KINASE_ATP; 1.
PS50011; PROTEIN_KINASE_DOM; 1.
PS00108; PROTEIN_KINASE_ST; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q4WPF2.
Genome annotation databases
GeneID 3509449; -.
KEGG afm:AFUA_4G09050; -.
Phylogenomic databases
HOGENOM Q4WPF2; -.
Other
ProtoNet Q4WPF2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Autophagy; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Protein transport; Serine/threonine-protein kinase; Transferase; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   973  973     Serine/threonine-protein kinase atg1. PRO_0000085639
DOMAIN   23   328  306     Protein kinase. 
NP_BIND   29    37  9     ATP (By similarity). 
ACT_SITE   166   166        Proton acceptor (By similarity). 
BINDING   52    52        ATP (By similarity). 
Sequence information
Length: 973 AA [This is the length of the unprocessed precursor] Molecular weight: 106080 Da [This is the MW of the unprocessed precursor] CRC64: 0E4A30848F9246BC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTSTHHSRRS RETPQPEMSI GRYTRLDEIG RGSFATVYQG VHTKTRTYVA IKSVNLSKLN 

        70         80         90        100        110        120 
KKLKDNLSSE IHILKGLYHP HIVALIDCHE TTSHIHLVME YCALGDLSLF IKRRDTLGDH 

       130        140        150        160        170        180 
RYTRDMIAKY PNPPGGALNE VVVRHFLKQL ASALKFLRDR NLIHRDIKPQ NLLLCPSPSS 

       190        200        210        220        230        240 
YRSGVTQVVP FKGSEDSFNP ATGLESLPLL KIADFGFARS LPATSLAETL CGSPLYMAPE 

       250        260        270        280        290        300 
ILRYEKYDAK ADLWSVGTVL YEMVVGKPPF RATNHVELLR KIEKGEDRIK FPEENPASDE 

       310        320        330        340        350        360 
IKALIRALLK RNPVERLNFP DFFQNGVITS PIPGLVADDL PSIPQGPPAD PETAEATPRP 

       370        380        390        400        410        420 
DSRSGATVPG GTEREREGPS LPKGDTGLTQ RPPSQNQRFG TPQTTTPMRR IGSGDRPPST 

       430        440        450        460        470        480 
PKESTPPMTY PQRPSAVSHA TAPGRQELVD RNATFTAMER QKGRNTFSEG SPQIDRQADK 

       490        500        510        520        530        540 
LREERERAAQ DVAFERDYVV VEKRAVEVNA FADELAHSPR IQGNISRGAQ TGALSRRSTV 

       550        560        570        580        590        600 
HGPTPSNPSP PQATVGKAMQ VLSGRSRADS MHNRQGSYER RYGQSPTSAT SAISKALNMA 

       610        620        630        640        650        660 
SGRLFGMGFS PPLAITKGGR SPPLAYNPFP AYPAHGSLMI GDGAKSNLAL DEDTKTVQIL 

       670        680        690        700        710        720 
EECATRSDVV YGFAEVKYKQ LVPLAPSVQT DPSSKLNLAG ERENPDSADG GLTVDAIVTL 

       730        740        750        760        770        780 
SEEALVLYVK ALSLLAKSMD IAGAWWARKN RGDGFGDSAM SRANGASTLA GTRINNVVQW 

       790        800        810        820        830        840 
IRNRFNEVLE KGEFVRLKLI EAQKRLPPDH PSHPDNHSVG SSLGSGASVD VVVSPGVSAE 

       850        860        870        880        890        900 
KLMYDRALEM SRTAAINELT GEDLSGCEIA YVTAIRMLEA VLENGEVPRF GQDKDDTSKD 

       910        920        930        940        950        960 
SDKIVLDAVQ ADERQVVIKL LTIQAVVASI RSRLAALRKK LAILAKRAPT PSANVPSKMA 

       970 
SSNPVSVGAT PPK 

Q4WPF2 in FASTA format

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