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UniProtKB/Swiss-Prot entry Q4JAM1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNLI_SULAC
Primary accession number Q4JAM1
Secondary accession numbers None
Integrated into Swiss-Prot on September 27, 2005
Sequence was last modified on August 2, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 22)
Name and origin of the protein
Protein name DNA ligase
Synonyms EC 6.5.1.1
Polydeoxyribonucleotide synthase [ATP]
Gene name
Name: lig
OrderedLocusNames: Saci_0788
From
Sulfolobus acidocaldarius [TaxID: 2285] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770;
DOI=10.1128/JB.187.14.4992-4999.2005; PubMed=15995215 [NCBI, ExPASy, EBI, Israel, Japan]
Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota.";
J. Bacteriol. 187:4992-4999(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000077; AAY80158.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_255451.1; -.
3D structure databases
ModBase Q4JAM1.
Enzyme and pathway databases
BioCyc SACI330779:SACI_0788-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003910; Molecular function: DNA ligase (ATP) activity (inferred from electronic annotation from HAMAP).
GO:0006310; Biological process: DNA recombination (inferred from electronic annotation from HAMAP).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00407; -; 1.
PBIL [Tree]
InterPro IPR000977; DNA_ligase.
IPR012309; DNA_ligase_A_C.
IPR012310; DNA_ligase_A_M.
IPR012308; DNA_ligase_A_N.
IPR016059; DNA_ligase_CS.
IPR012340; NA-bd_OB-fold.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
Pfam PF04679; DNA_ligase_A_C; 1.
PF01068; DNA_ligase_A_M; 1.
PF04675; DNA_ligase_A_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00574; dnl1; 1.
PROSITE PS00697; DNA_LIGASE_A1; 1.
PS00333; DNA_LIGASE_A2; 1.
PS50160; DNA_LIGASE_A3; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q4JAM1.
Genome annotation databases
GeneID 3473850; -.
GenomeReviews CP000077_GR; Saci_0788.
KEGG sai:Saci_0788; -.
NMPDR fig|330779.3.peg.488; -.
Phylogenomic databases
HOGENOM Q4JAM1; -.
Genome annotation databases
CMR Q4JAM1; Saci_0788.
Other
ProtoNet Q4JAM1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA replication; Ligase; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   598  598     DNA ligase. PRO_0000059616
ACT_SITE   260   260        N6-AMP-lysine intermediate (By similarity). 
Sequence information
Length: 598 AA [This is the length of the unprocessed precursor] Molecular weight: 67576 Da [This is the MW of the unprocessed precursor] CRC64: D8C6D946CF2D76A4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEFKLIAEYF DRLEKISSRI QLTALLTDLL KKSDKDVIDK VIYITQGKLW PDFFEKPEIG 

        70         80         90        100        110        120 
LGEKLMIKAL SVSTNIKEDE IEKQLRILGD LGEVAYKLKR TNSSQNVLSY LGSTKVTKLT 

       130        140        150        160        170        180 
VEEVYESLSK IALSEGEGSR DMKIRSLAGL LKKADPLEAK YIIRFIDGRL RVGIGDATIM 

       190        200        210        220        230        240 
DALANVFGGG TAARPLIERA YNLRADLGNI AKLLAENGIE TIKSIKPEVG IPIRPMLAER 

       250        260        270        280        290        300 
LTDPSEILAK VGGKGIVDYK YDGERAQIHK KGEKVYIFSR RLENITRQYP DVVEYIKNSI 

       310        320        330        340        350        360 
KSNEVILEGE IVAIDKESGE ILPFQNLMHR KRKNDIGEAI KEYPVNVYLF DLMYNDGEDY 

       370        380        390        400        410        420 
TQKPLPDRRE KLEEIVTQND IVKVADHKYI DKVNELVEYF HQAISDGTEG VIVKSIGKDS 

       430        440        450        460        470        480 
IYQAGARGFL WIKLKKDYQS EMADSVDLVI VGAFYGRGKR GGKLSSLLMA AYDPDKDTFY 

       490        500        510        520        530        540 
TVCKVASGFS DAELEEVQKM LSEAKLDKKD PRVESEIQPD IWVKPKYVAE IIGAEITLSP 

       550        560        570        580        590 
LHTCCKGVVS EEAGLSIRFP RFIRWRDDKS VEEATTPNEI LEMYQSRLKK KVEDITET 

Q4JAM1 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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