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UniProtKB/Swiss-Prot entry Q4FRX3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAO1_PSYA2
Primary accession number Q4FRX3
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on August 30, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 24)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: Psyc_1387
From
Psychrobacter arcticus (strain DSM 17307 / 273-4) [TaxID: 259536] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Moraxellaceae; Psychrobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
NASA Astrobiology Institute;
Ayala-del-Rio H.L., Chain P., Ponder M.A., Di Bartolo G., Ivanova N., Bergholz P.W., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J.A., Zarka D., Larimer F., Richardson P., Thomashow M.F., Tiedje J.M.;
"Complete sequence of Psychrobacter arcticum 273-4.";
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000082; AAZ19235.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_264669.1; -.
3D structure databases
ModBase Q4FRX3.
Enzyme and pathway databases
BioCyc PARC259536:PSYC_1387-MON; -.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q4FRX3.
Genome annotation databases
GeneID 3515345; -.
GenomeReviews CP000082_GR; Psyc_1387.
KEGG par:Psyc_1387; -.
NMPDR fig|259536.4.peg.1046; -.
Phylogenomic databases
HOGENOM Q4FRX3; -.
Genome annotation databases
CMR Q4FRX3; Psyc_1387.
Other
ProtoNet Q4FRX3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   560  560     NAD-dependent malic enzyme. PRO_0000160227
ACT_SITE   100   100        Proton donor (By similarity). 
ACT_SITE   171   171        Proton acceptor (By similarity). 
METAL   242   242        Divalent metal cation (By similarity). 
METAL   243   243        Divalent metal cation (By similarity). 
METAL   266   266        Divalent metal cation (By similarity). 
BINDING   153   153        NAD (By similarity). 
BINDING   266   266        NAD (By similarity). 
BINDING   413   413        NAD (By similarity). 
SITE   266   266  1     Important for activity (By similarity). 
Sequence information
Length: 560 AA [This is the length of the unprocessed precursor] Molecular weight: 62676 Da [This is the MW of the unprocessed precursor] CRC64: 2AF5AE968858C1D2 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MPNQRPLYIP FSGPALLETP LLNKGSAFSS EERDSFNLTG LLPHNIETIE EQSLRAYHQL 

        70         80         90        100        110        120 
RSFTTDIDKH IYLRNIQDTN ETLFHHLIEQ HIEEVMPLIY TPTVGQACEK FSQIYRRKRG 

       130        140        150        160        170        180 
LFISYPDRHK IDDMLQNATK QKVKVIVVTD GERILGLGDQ GIGGMGIPIG KLALYTACGG 

       190        200        210        220        230        240 
ISPAYCLPIL LDVGTNNQQL LDDPMYMGWR NQRISGDEYN EFVDLFIQAV KRRWPEVLLQ 

       250        260        270        280        290        300 
FEDFAQENAT PLLNRYRDQL CCFNDDIQGT AAVSVGTLIA ACLNKGQKLS QQKIAFLGAG 

       310        320        330        340        350        360 
SAGCGIAEHI IRQMQREGLT EEQARKQVFM VDRYGLLTDS MTELQKFQAP LVQKESAIES 

       370        380        390        400        410        420 
WDKSQKLGLA QVVKQAKITV LFGVSGQKGL FTREVIEALC VNTEHPIVLP LSNPTSRVEA 

       430        440        450        460        470        480 
TPQEVTSWSR GKAIVATGSP FPNTTFEDQS FEISQCNNSY IFPGIGLGVL AAHATGISDN 

       490        500        510        520        530        540 
MLMSASQALA DISMEYEKAP GAILPPIKFI REISEKIAYA VALQAIEDKL ALPVTAENLE 

       550        560 
RRLKANFWLP RYHNYRRTSF
Q4FRX3 in FASTA format

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