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UniProtKB/Swiss-Prot entry Q46BA3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNLI_METBF
Primary accession number Q46BA3
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on September 13, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 26)
Name and origin of the protein
Protein name DNA ligase
Synonyms EC 6.5.1.1
Polydeoxyribonucleotide synthase [ATP]
Gene name
Name: lig
OrderedLocusNames: Mbar_A1899
From
Methanosarcina barkeri (strain Fusaro / DSM 804) [TaxID: 269797] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.00810-06; PubMed=16980466 [NCBI, ExPASy, EBI, Israel, Japan]
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.;
"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes.";
J. Bacteriol. 188:7922-7931(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000099; AAZ70839.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_305419.1; -.
3D structure databases
ModBase Q46BA3.
Enzyme and pathway databases
BioCyc MBAR269797:MBAR_A1899-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003910; Molecular function: DNA ligase (ATP) activity (inferred from electronic annotation from HAMAP).
GO:0006310; Biological process: DNA recombination (inferred from electronic annotation from HAMAP).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00407; -; 1.
PBIL [Tree]
InterPro IPR000977; DNA_ligase.
IPR012309; DNA_ligase_A_C.
IPR012310; DNA_ligase_A_M.
IPR012308; DNA_ligase_A_N.
IPR016059; DNA_ligase_CS.
IPR012340; NA-bd_OB-fold.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
Pfam PF04679; DNA_ligase_A_C; 1.
PF01068; DNA_ligase_A_M; 1.
PF04675; DNA_ligase_A_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00574; dnl1; 1.
PROSITE PS00697; DNA_LIGASE_A1; 1.
PS00333; DNA_LIGASE_A2; FALSE_NEG.
PS50160; DNA_LIGASE_A3; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q46BA3.
Genome annotation databases
GeneID 3624300; -.
GenomeReviews CP000099_GR; Mbar_A1899.
KEGG mba:Mbar_A1899; -.
NMPDR fig|269797.3.peg.2831; -.
Phylogenomic databases
HOGENOM Q46BA3; -.
Genome annotation databases
CMR Q46BA3; Mbar_A1899.
Other
ProtoNet Q46BA3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA replication; Ligase; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   568  568     DNA ligase. PRO_1000049868
ACT_SITE   256   256        N6-AMP-lysine intermediate (By similarity). 
Sequence information
Length: 568 AA [This is the length of the unprocessed precursor] Molecular weight: 63176 Da [This is the MW of the unprocessed precursor] CRC64: CF22D6D1E1A08B95 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTSFREFAET CQAIEKISST IDTTSRVADL LKKVDVEELP IATHFIMSEV FPAWSGEQLG 

        70         80         90        100        110        120 
IGTSLLYVSL SKASGMPVKS IESLIRTTGD IGDTALLILK EKRKNQVTFS SFFEEQPELS 

       130        140        150        160        170        180 
ITEVYNRFKI ASEASGKGSQ DIKIKNLQFL FTSSTPREAK YISRLALEEL RIGVGEGVVR 

       190        200        210        220        230        240 
DAIAKAFSVP VDVVEHAFMV TNDLGIVAAT AKDGGVEALE SLGIEINRPI KMMLSQISPD 

       250        260        270        280        290        300 
IVADIKEMKE AAIEWKFDGA RVQVHKAGDS VMLFSRKLEN VTNSLPDLVE IIRKHVKAES 

       310        320        330        340        350        360 
AILDGEAVAV DENGRPRAFQ EILKRFRRKY DVEEKALGIP IQLNLFDIMY LNGKTLIDLP 

       370        380        390        400        410        420 
LIERRKALES CVESSVEDSK SISVDKQVIT GDLDLIEKIY KEALDAGHEG VMVKNPNSFY 

       430        440        450        460        470        480 
SPGKRGKNWL KKKPLMETLD LVVVGAEWGF GRRANLLGSY TVACYDPKTL RFLQVGKVGT 

       490        500        510        520        530        540 
GLTDDQLKEL TEILSGLMEG GEAGGIFAIR PKIVLEIAFE EIQKSPNYDS GFALRFPRFI 

       550        560 
RIRDDKDPEE ADTIQRIGKV YSQQLKRL
Q46BA3 in FASTA format

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