[1]	NUCLEOTIDE SEQUENCE [MRNA]. STRAIN=cv. Wando; TISSUE=Leaf; Williamson C.L., To L., Slocum R.D.; "Characterization of a cDNA encoding a third aspartate transcarbamoylase (pyrB3) from pea."; (er) Plant Gene Register PGR96-063.

Comments

CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
ENZYME REGULATION: Allosterically regulated by UMP.
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6 .
SUBUNIT: Homotrimer (Potential).
SUBCELLULAR LOCATION: Plastid, chloroplast.
SIMILARITY: Belongs to the ATCase/OTCase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U05293; AAB67857.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

T06425; T06425.

3D structure databases

HSSP

P00479; 1GQ3. [HSSP ENTRY / SWISS-3DIMAGE / PDB]

ModBase

Q43064.

Family and domain databases

InterPro

IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.

Pfam

PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.

PRINTS

PR00100; AOTCASE.
PR00101; ATCASE.

TIGRFAMs

TIGR00670; asp_carb_tr; 1.

PROSITE

PS00097; CARBAMOYLTRANSFERASE; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Allosteric enzyme; Chloroplast; Plastid; Pyrimidine biosynthesis; Transferase; Transit peptide.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`TRANSIT`	`1 69`	`69`	`Chloroplast (Potential).`
`CHAIN`	`70 391`	`322`	`Aspartate carbamoyltransferase 3, chloroplastic.`	`PRO_0000020351`

Sequence information

Length: 391 AA [This is the length of the unprocessed precursor]

Molecular weight: 44344 Da [This is the MW of the unprocessed precursor]

CRC64: 5693EBC634FAEBA9 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTASSSLFSC SMHMEVLTPK ISKWPKDFVS CHSKISYVET NYLKSTCYPI SRFLCINNLS 

        70         80         90        100        110        120 
KCDKMIKTRQ RDGIHCFSEG QKFQLDDVIE AQQFDRDILN AIFEIARDME NIERNSPESQ 

       130        140        150        160        170        180 
ILKGYLMATL FYEPSTRTRL SFESAMRRLG GEVLTTENAR EFSSAAKGET LEDTIRTVEG 

       190        200        210        220        230        240 
YSDLIVLRHF ESGAARRAAA IAGIPIVNAG DGPGQHPSQA LLDVYTIERE IGKLDGIKVG 

       250        260        270        280        290        300 
LVGDLANGRT VRSLAYLLAK YKDVKIYFVS PEVVKMKDDI KDYLTSKGVD WEESSDLVEV 

       310        320        330        340        350        360 
ASECDVVYQT RIQKERFGER LDLYEKARGK FIVNQNILNA MQRHAVIMHP LPRLDEITVD 

       370        380        390 
VDADPRAAYF RQAKYGLYIR MALLKLLLVG W

Q43064 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools