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UniProtKB/TrEMBL entry Q3TJ94


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name Q3TJ94_MOUSE
Primary accession number Q3TJ94
Secondary accession numbers None
Integrated into TrEMBL on October 11, 2005
Sequence was last modified on October 11, 2005 (Sequence version 1)
Annotations were last modified on    September 23, 2008 (Entry version 41)
Name and origin of the protein
Protein name 12 days pregnant adult female placenta cDNA, RIKEN full-length enriched library, clone:I530018P09 product:coagulation factor II, full insert sequence
Synonyms None
Gene name
Name: F2
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J;
TISSUE=Placenta;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AK167532; BAE39601.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_034298.1; -.
UniGene Mm.89048
3D structure databases
ModBase Q3TJ94.
Organism-specific databases
MGI MGI:88380; F2.
Gene expression databases
ArrayExpress Q3TJ94; -.
Ontologies
GO
GO:0005576; Cellular component: extracellular region (inferred from electronic annotation from InterPro).
GO:0005509; Molecular function: calcium ion binding (inferred from electronic annotation from InterPro).
GO:0003809; Molecular function: thrombin activity (inferred from electronic annotation from InterPro).
GO:0007596; Biological process: blood coagulation (inferred from electronic annotation from InterPro).
GO:0006508; Biological process: proteolysis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR002383; Coagulation_factor_Gla.
IPR000001; Kringle.
IPR001254; Peptidase_S1_S6.
IPR001314; Peptidase_S1A.
IPR012051; Peptidase_S1A_pr.
IPR003966; Peptidase_S1A_prothrombin.
IPR000294; VitK_dep_GLA.
Graphical view of domain structure.
Gene3D G3DSA:2.40.20.10; Kringle; 2.
PANTHER PTHR19355:SF61; Peptidase_S1A_pr; 1.
Pfam PF00594; Gla; 1.
PF00051; Kringle; 2.
PF00089; Trypsin; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001149; Thrombin; 1.
PRINTS PR00722; CHYMOTRYPSIN.
PR00001; GLABLOOD.
PR00018; KRINGLE.
PR01505; PROTHROMBIN.
ProDom PD000395; Kringle; 2.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00069; GLA; 1.
SM00130; KR; 2.
SM00020; Tryp_SPc; 1.
SMART graphical view of domain structure.
PROSITE PS00011; GLA_1; 1.
PS50998; GLA_2; 1.
PS00021; KRINGLE_1; 2.
PS50070; KRINGLE_2; 2.
PS50240; TRYPSIN_DOM; 1.
PS00134; TRYPSIN_HIS; UNKNOWN_1.
PS00135; TRYPSIN_SER; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
Ensembl ENSMUSG00000027249; Mus musculus. [Contig view]
GeneID 14061; -.
KEGG mmu:14061; -.
NMPDR fig|10090.3.peg.6405; -.
Phylogenomic databases
HOVERGEN Q3TJ94; -.
Other
SOURCE F2; Mus musculus.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Hydrolase; Kringle; Protease; Serine protease.
Features
None
Sequence information
Length: 618 AA Molecular weight: 70269 Da CRC64: B89F719AAFD601E0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSHVRGLGLP GCLALAALVS LVHSQHVFLA PQQALSLLQR VRRANSGFLE ELRKGNLERE 

        70         80         90        100        110        120 
CVEEQCSYEE AFEALESPQD TDVFWAKYTV CDSVRKPRET FMDCLEGRCA MDLGVNYLGT 

       130        140        150        160        170        180 
VNVTHTGIQC QLWRSRYPHK PEINSTTHPG ADLKENFCRN PDSSTTGPWC YTTDPTVRRE 

       190        200        210        220        230        240 
ECSVPVCGQE GRTTVVMTPR SGGSKDNLSP PLGQCLTERG RLYQGNLAVT TLGSPCLPWN 

       250        260        270        280        290        300 
SLPAKTLSKY QDFDPEVKLV ENFCRNPDWD EEGAWCYVAG QPGDFEYCNL NYCEEAVGEE 

       310        320        330        340        350        360 
NYDVDESIAG RTTDAEFHTF FNEKTFGLGE ADCGLRPLFE KKSLKDTTEK ELLDSYIDGR 

       370        380        390        400        410        420 
IVEGWDAEKG IAPWQVMLFR KSPQELLCGA SLISDRWVLT AAHCILYPPW DKNFTENDLL 

       430        440        450        460        470        480 
VRIGKHSRTR YERNVEKISM LEKIYVHPRY NWRENLDRDI ALLKLKKPVP FSDYIHPVCL 

       490        500        510        520        530        540 
PDKQTVTSLL RAGYKGRVTG WGNLRETWTT NINEIQPSVL QVVNLPIVER PVCKASTRIR 

       550        560        570        580        590        600 
ITDNMFCAGF KVNDTKRGDA CEGDSGGPFV MKSPFNNRWY QMGIVSWGEG CDRKGKYGFY 

       610 
THVFRLKRWI QKVIDQFG 

Q3TJ94 in FASTA format

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View entry in raw text format (no links)
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