NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.;
"Complete sequence of Anabaena variabilis ATCC 29413.";
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6 .
SIMILARITY: Belongs to the ATCase/OTCase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000117; ABA20798.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_321693.1; -.

3D structure databases

ModBase

Q3MDY8.

Enzyme and pathway databases

BioCyc

AVAR240292:AVA_1174-MON; -.

Ontologies

GO:0004070;	Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221;	Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00001; -; 1.
PBIL [Tree]

InterPro

IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.

Pfam

PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.

PRINTS

PR00100; AOTCASE.
PR00101; ATCASE.

TIGRFAMs

TIGR00670; asp_carb_tr; 1.

PROSITE

PS00097; CARBAMOYLTRANSFERASE; 1.

BLOCKS

Q3MDY8.

Genome annotation databases

GeneID

3683312; -.

GenomeReviews

CP000117_GR; Ava_1174.

KEGG

ava:Ava_1174; -.

NMPDR

fig|240292.3.peg.1699; -.

Phylogenomic databases

HOGENOM

Q3MDY8; -.

Genome annotation databases

CMR

Q3MDY8; Ava_1174.

Other

ProtoNet

Q3MDY8.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Pyrimidine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 333`	`333`		`Aspartate carbamoyltransferase.`	`PRO_0000321069`

Sequence information

Length: 333 AA [This is the length of the unprocessed precursor]

Molecular weight: 36582 Da [This is the MW of the unprocessed precursor]

CRC64: 7B6D387DA0A1E2AF [This is a checksum on the sequence]

        10         20         30         40         50         60 
MPTSTWNRHH VLSLADFTAA EYDIVLKTAA SFQEVLSRRT KKVPALQGQV VANLFFEPST 

        70         80         90        100        110        120 
RTRSSFELAA KRLSADTLNF AASTSSMTKG ETILDTAKTY LAMGTDIMVI RHKEAGVPNA 

       130        140        150        160        170        180 
IAQEMDRLGV RVSVLNAGDG QHEHPSQGLL DLFTICSLVD PANPRLELLQ GKKIAIVGDI 

       190        200        210        220        230        240 
LHSRVARSNI WSLIASGAQV HLAAPPTLLP KLFAEYIFGE ETAPPGQLFI HWQLEPALQD 

       250        260        270        280        290        300 
ADFVMTLRLQ KERMTAHLLP SLREYHQLFG ITRAKLQLCQ PNVKVLHPGP VNRGVEISSD 

       310        320        330 
LMDDPEFSLI QSQVTSGVAV RMALLYLIGS GKT

Q3MDY8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools