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UniProtKB/Swiss-Prot entry Q3IPX0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNLI_NATPD
Primary accession number Q3IPX0
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on November 8, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 25)
Name and origin of the protein
Protein name DNA ligase
Synonyms EC 6.5.1.1
Polydeoxyribonucleotide synthase [ATP]
Gene name
Name: lig
OrderedLocusNames: NP3474A
From
Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) [TaxID: 348780] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Natronomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1101/gr.3952905; PubMed=16169924 [NCBI, ExPASy, EBI, Israel, Japan]
Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J., Oesterhelt D.;
"Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis.";
Genome Res. 15:1336-1343(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR936257; CAI49828.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_327383.1; -.
3D structure databases
ModBase Q3IPX0.
Enzyme and pathway databases
BioCyc NPHA348780:NP3474A-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003910; Molecular function: DNA ligase (ATP) activity (inferred from electronic annotation from HAMAP).
GO:0006310; Biological process: DNA recombination (inferred from electronic annotation from HAMAP).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00407; -; 1.
PBIL [Tree]
InterPro IPR000977; DNA_ligase.
IPR012309; DNA_ligase_A_C.
IPR012310; DNA_ligase_A_M.
IPR012308; DNA_ligase_A_N.
IPR016059; DNA_ligase_CS.
IPR012340; NA-bd_OB-fold.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
Pfam PF04679; DNA_ligase_A_C; 1.
PF01068; DNA_ligase_A_M; 1.
PF04675; DNA_ligase_A_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00574; dnl1; 1.
PROSITE PS00697; DNA_LIGASE_A1; 1.
PS00333; DNA_LIGASE_A2; FALSE_NEG.
PS50160; DNA_LIGASE_A3; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q3IPX0.
Genome annotation databases
GeneID 3702886; -.
GenomeReviews CR936257_GR; NP3474A.
KEGG nph:NP3474A; -.
NMPDR fig|348780.3.peg.1913; -.
Phylogenomic databases
HOGENOM Q3IPX0; -.
Genome annotation databases
CMR Q3IPX0; NP3474A.
Other
ProtoNet Q3IPX0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA replication; Ligase; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   548  548     DNA ligase. PRO_1000049874
ACT_SITE   254   254        N6-AMP-lysine intermediate (By similarity). 
Sequence information
Length: 548 AA [This is the length of the unprocessed precursor] Molecular weight: 58865 Da [This is the MW of the unprocessed precursor] CRC64: 621F22FEEA73D814 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MEFAEFAARA AEIESEPADL ETVDLVATLC ADAGDDLGTV ARFVQGRVFP AHDSTKLDIG 

        70         80         90        100        110        120 
PSLCYEALAK AAGPNVDSDD IERRLAEVGE IGAVAESLDL GGQQGLAAFG GGTDREALTV 

       130        140        150        160        170        180 
SGVEETLQAL AAAAGDGSTD AKRDRLFDLF NRAEPTEARF LARLVLGEMR VGVGEGTVRD 

       190        200        210        220        230        240 
AIAAAFEVPE PDVERALQVA NDCGLVAETA RDDGAAGLDD IGLVVGRPVK AMLAQAGTAV 

       250        260        270        280        290        300 
EALDEWGTAA VETKYDGARV QVHYDGDSAR LFSRNLEEVT EPLPEVVEFV EQSLSVPAIL 

       310        320        330        340        350        360 
DGEVVAVDDD GTPRPFQEIL RRFRRKHDVA AAREDVSVEL YAFDCLHVDG EDLLDTPLSE 

       370        380        390        400        410        420 
RHDRLESLLA DGVSPLSYAD DADEVADIEA DALDAGHEGI MLKNPDSTYT PGSRGKNWLK 

       430        440        450        460        470        480 
RKPDVETLDL VVTGAEWGEG RRANLLGTFV VSARADDGYE PVGKVATGIT DEELERLHER 

       490        500        510        520        530        540 
LQPHVRTEDG TDVDIEPAVV FEVGYEEIQQ SPTYGSGYAL RFPRFVGVRE DKSPSDADSL 


ERIDRLTS
Q3IPX0 in FASTA format

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