ID   UFO_ARATH               Reviewed;         442 AA.
AC   Q39090; Q4PT17; Q9FYI4;
DT   09-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   09-MAY-2003, sequence version 2.
DT   22-JUL-2008, entry version 62.
DE   RecName: Full=Protein UNUSUAL FLORAL ORGANS;
DE   AltName: Full=F-box only protein 1;
DE            Short=AtFBX1;
GN   Name=UFO; Synonyms=FBX1; OrderedLocusNames=At1g30950;
GN   ORFNames=F17F8.16;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
RC   STRAIN=cv. Landsberg erecta;
RX   MEDLINE=96172795; PubMed=8589630; DOI=10.1105/tpc.7.9.1501;
RA   Ingram G.C., Goodrich J., Wilkinson M.D., Simon R., Haughn G.W.,
RA   Coen E.S.;
RT   "Parallels between UNUSUAL FLORAL ORGANS and FIMBRIATA, genes
RT   controlling flower development in Arabidopsis and Antirrhinum.";
RL   Plant Cell 7:1501-1510(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   MEDLINE=21016719; PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S.,
RA   White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y.,
RA   Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W.,
RA   Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K.,
RA   Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y.,
RA   Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L.,
RA   Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E.,
RA   Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B.,
RA   Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P.,
RA   Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A.,
RA   Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I.,
RA   Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D.,
RA   Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M.,
RA   Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M.,
RA   Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   FUNCTION.
RX   MEDLINE=96152196; PubMed=8565821;
RA   Krizek B.A., Meyerowitz E.M.;
RT   "The Arabidopsis homeotic genes APETALA3 and PISTILLATA are sufficient
RT   to provide the B class organ identity function.";
RL   Development 122:11-22(1996).
RN   [5]
RP   FUNCTION, AND DEVELOPMENTAL STAGE.
RX   MEDLINE=97169338; PubMed=9016705; DOI=10.1016/S0960-9822(06)00053-4;
RA   Lee I., Wolfe D.S., Nilsson O., Weigel D.;
RT   "A LEAFY co-regulator encoded by UNUSUAL FLORAL ORGANS.";
RL   Curr. Biol. 7:95-104(1997).
RN   [6]
RP   FUNCTION.
RX   MEDLINE=20074783; PubMed=10607296;
RX   DOI=10.1046/j.1365-313x.1999.00617.x;
RA   Samach A., Klenz J.E., Kohalmi S.E., Risseeuw E., Haughn G.W.,
RA   Crosby W.L.;
RT   "The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box
RT   protein required for normal patterning and growth in the floral
RT   meristem.";
RL   Plant J. 20:433-445(1999).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   MEDLINE=20530940; PubMed=11077244; DOI=10.1016/S1360-1385(00)01769-6;
RA   Xiao W., Jang J.-C.;
RT   "F-box proteins in Arabidopsis.";
RL   Trends Plant Sci. 5:454-457(2000).
RN   [8]
RP   SUBUNIT.
RX   MEDLINE=21417209; PubMed=11526079;
RA   Zhao D., Yu Q., Chen M., Ma H.;
RT   "The ASK1 gene regulates B function gene expression in cooperation
RT   with UFO and LEAFY in Arabidopsis.";
RL   Development 128:2735-2746(2001).
RN   [9]
RP   INTERACTION WITH SKP1, AND DOMAIN.
RX   MEDLINE=22735882; PubMed=12826617; DOI=10.1073/pnas.1033043100;
RA   Durfee T., Roe J.L., Sessions R.A., Inouye C., Serikawa K.,
RA   Feldmann K.A., Weigel D., Zambryski P.C.;
RT   "The F-box-containing protein UFO and AGAMOUS participate in
RT   antagonistic pathways governing early petal development in
RT   Arabidopsis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8571-8576(2003).
CC   -!- FUNCTION: Considered as a meristem identity factor required for
CC       normal growth of the young floral meristem. Acts together with
CC       LEAFY to positively regulate the B class floral homeotic genes
CC       APETALA3 and PISTILLATA. In this way, operates as a region-
CC       specific regulator for petal and stamen development.
CC       Alternatively, may play a role as a negative regulator of the C
CC       class floral homeotic genes. Interacts together with the SKP1-like
CC       protein ASK1 to form a ubiquitin E3 ligase complex and could
CC       indirectly promote the ubiquitination and degradation of specific
CC       proteins controlling the floral primordia development like
CC       repressors of B class floral homeotic genes.
CC   -!- SUBUNIT: Part of a putative SCF (SKP1/Cullin/F-box) ubiquitin
CC       ligase complex. Interacts with SKP1.
CC   -!- INTERACTION:
CC       O49484:AT4g34210; NbExp=2; IntAct=EBI-590758, EBI-401185;
CC       Q00958:LFY; NbExp=3; IntAct=EBI-590758, EBI-1644366;
CC       Q39255:SKP1A; NbExp=4; IntAct=EBI-590758, EBI-532357;
CC       Q9FHW7:SKP1B; NbExp=2; IntAct=EBI-590758, EBI-604076;
CC   -!- SUBCELLULAR LOCATION: Nucleus (Probable).
CC   -!- DEVELOPMENTAL STAGE: Detected early throughout the shoot apical
CC       meristem, but not in the emerging leaf primordia. Restricted later
CC       to the junction between sepal and petal primordia.
CC   -!- MISCELLANEOUS: Mutations in the UFO gene result in the formation
CC       of unusual floral organs.
CC   -!- SIMILARITY: Contains 1 F-box domain.
CC   -!- WEB RESOURCE: Name=PlantsUBQ; Note=A functional genomics database
CC       for the ubiquitin/26S proteasome proteolytic pathway in plants;
CC       URL="http://plantsubq.genomics.purdue.edu/";
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DR   EMBL; X89224; CAA61508.1; -; Genomic_DNA.
DR   EMBL; AC000107; AAF98199.1; -; Genomic_DNA.
DR   EMBL; DQ056469; AAY78626.1; -; mRNA.
DR   PIR; S57710; S57710.
DR   RefSeq; NP_564368.1; -.
DR   UniGene; At.51845; -.
DR   IntAct; Q39090; -.
DR   GeneID; 839982; -.
DR   GenomeReviews; CT485782_GR; AT1G30950.
DR   KEGG; ath:AT1G30950; -.
DR   NMPDR; fig|3702.1.peg.3439; -.
DR   TAIR; At1g30950; -.
DR   ArrayExpress; Q39090; -.
DR   GermOnline; AT1G30950; Arabidopsis thaliana.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   InterPro; IPR001810; F-box.
DR   Pfam; PF00646; F-box; 1.
DR   SMART; SM00256; FBOX; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   1: Evidence at protein level;
KW   Activator; Complete proteome; Developmental protein; Differentiation;
KW   Flowering; Nucleus; Transcription; Transcription regulation;
KW   Ubl conjugation pathway.
FT   CHAIN         1    442       Protein UNUSUAL FLORAL ORGANS.
FT                                /FTId=PRO_0000119966.
FT   DOMAIN       44     90       F-box.
FT   CONFLICT     44     44       G -> C (in Ref. 1; CAA61508).
SQ   SEQUENCE   442 AA;  49047 MW;  6E5C38B0F92AE8B7 CRC64;
     MDSTVFINNP SLTLPFSYTF TSSSNSSTTT STTTDSSSGQ WMDGRIWSKL PPPLLDRVIA
     FLPPPAFFRT RCVCKRFYSL LFSNTFLETY LQLLPLRHNC FLFFKHKTLK SYIYKRGGTN
     DDDSNKAEGF LFDPNEIRWY RLSFAYIPSG FYPSGSSGGL VSWVSEEAGL KTILLCNPLV
     GSVSQLPPIS RPRLFPSIGL SVTPTSIDVT VAGDDLISPY AVKNLSSESF HVDAGGFFSL
     WAMTSSLPRL CSLESGKMVY VQGKFYCMNY SPFSVLSYEV TGNRWIKIQA PMRRFLRSPS
     LLESKGRLIL VAAVEKSKLN VPKSLRLWSL QQDNATWVEI ERMPQPLYTQ FAAEEGGKGF
     ECVGNQEFVM IVLRGTSLQL LFDIVRKSWL WVPPCPYSGS GGGSSGGGSD GEVLQGFAYD
     PVLTTPVVSL LDQLTLPFPG VC
//