NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/ismej.2007.46; PubMed=18059494 [NCBI, ExPASy, EBI, Israel, Japan]
Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses.";
ISME J. 1:703-713(2007).

Comments

CATALYTIC ACTIVITY: 2,3,4,5-tetrahydrodipicolinate + NAD(P)⁺ = 2,3-dihydrodipicolinate + NAD(P)H.
PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; tetrahydrodipicolinate from L-aspartate: step 4/4 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000239; ABC99485.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_474748.1; -.

3D structure databases

ModBase

Q2JUX2.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0005488;	Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0008839;	Molecular function: dihydrodipicolinate reductase activity (inferred from electronic annotation from InterPro).
GO:0019877;	Biological process: diaminopimelate biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR000846; DapB.
IPR011770; DapB_bac/pln.
IPR016040; NAD(P)-bd_dom.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR20836; DapB_bac/pln; 1.

Pfam

PF05173; DapB_C; 1.
PF01113; DapB_N; 1.
Pfam graphical view of domain structure.

ProDom

PD004105; DapB; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGRFAMs

TIGR00036; dapB; 1.

PROSITE

PS01298; DAPB; 1.

Genome annotation databases

GeneID

3899474; -.

GenomeReviews

CP000239_GR; CYA_1305.

KEGG

cya:CYA_1305; -.

TIGR

CYA_1305; -.

Phylogenomic databases

HOGENOM

Q2JUX2; -.

OMA

Q2JUX2; TCIKTAE.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Complete proteome; Cytoplasm; Diaminopimelate biosynthesis; Lysine biosynthesis; NADP; Oxidoreductase.

Features

None

Sequence information

Length: 293 AA

Molecular weight: 31218 Da

CRC64: AD4282444CE33E5D [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTTAVEQKRR EEGAAIGEGT AASEPIPVLV VGALGKMGRE VVRAVAQTPD MKLVGAVARS 

        70         80         90        100        110        120 
QLGSDIGEVL GLGSLGVEIT DDLAGQLLRL SQRSARGVMV DFTHPRSVYE NVRSAIAFGV 

       130        140        150        160        170        180 
RPVVGTTGLT PEQVERLRDL ADKSGVGCLI APNFAIGMIL LQQMALQAAQ YFDHVEIVEL 

       190        200        210        220        230        240 
HHNRKVDAPS GTALQTAQRL GQLGKAFNPP EVEEKELIPG SRGGIPGPNI PIHSVRLPGL 

       250        260        270        280        290 
IAHQEVIFGG MGQTLTLRHD ITDRMAFMPG VILGIRKVLQ LKGLVYGLEQ VLS

Q2JUX2 in FASTA format

View entry in raw text format (no links)
Request for annotation of this UniProtKB/TrEMBL entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools